Fluoride-induced changes in carbohydrate metabolism in the tissues of fresh water crab Barytelphusa querini

Exposure of fresh water crab Barytelphusa querini to a sublethal concentration of NaF (30 ppm) caused significant alterations in the carbohydrate metabolism. In an exposure span of 15 days the crab was observed to have marked depletion in glycogen and total free sugar levels. A significant elevation in "active" and "total" glycogen phosphorylase activity was observed. The activity changes of lactate dehydrogenase reflected changes in tissue lactate levels and succinate dehydrogenase activity had a tissue specificity.