Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Applications of Molecular Taxonomy01:20

Applications of Molecular Taxonomy

644
Molecular taxonomy has revolutionized the understanding and classification of bacteria, providing precise insights into their diversity, evolutionary relationships, and ecological roles. By utilizing molecular techniques such as DNA sequencing and fingerprinting, researchers have made significant strides in various fields related to bacterial studies.Resolving Taxonomic AmbiguitiesMolecular taxonomy has been instrumental in distinguishing closely related bacterial species initially thought to...
644
Genomics02:02

Genomics

41.4K
Genomics is the science of genomes: it is the study of all the genetic material of an organism. In humans, the genome consists of information carried in 23 pairs of chromosomes in the nucleus, as well as mitochondrial DNA. In genomics, both coding and non-coding DNA is sequenced and analyzed. Genomics allows a better understanding of all living things, their evolution, and their diversity. It has a myriad of uses: for example, to build phylogenetic trees, to improve productivity and...
41.4K
Pharmacogenetics of Drug Metabolism: Overview01:27

Pharmacogenetics of Drug Metabolism: Overview

87
Genetic polymorphism in drug metabolism is crucial to the inter-individual variability observed in drug responses. Drug metabolism primarily involves the chemical modification of drugs and other xenobiotics to enhance their elimination by increasing their polarity. Two main classes of enzymes mediate this biotransformation process: Phase I enzymes, primarily cytochrome P450s, catalyze oxidation and reduction reactions, while other enzymes, such as esterases, mediate hydrolysis, and Phase II...
87
Modern Molecular Taxonomy01:29

Modern Molecular Taxonomy

812
Advancements in molecular biology have revolutionized the identification and characterization of bacteria, with multiple methods leveraging DNA sequencing for enhanced precision. As sequencing technologies improve and costs decline, these approaches are increasingly used in clinical, environmental, and evolutionary studies.Multilocus Sequence Typing (MLST) examines several housekeeping genes, essential chromosomal genes encoding cellular functions, to distinguish strains. Approximately...
812
Pharmacogenetics and Pharmacogenomics: Overview01:29

Pharmacogenetics and Pharmacogenomics: Overview

110
Pharmacogenetics and pharmacogenomics examine how genetic factors influence an individual's response to drugs. While pharmacogenetics focuses on the impact of specific genetic variants on drug effects, pharmacogenomics takes a broader approach, studying how genetic variation across populations contributes to differences in drug responses. These fields aim to explain why individuals may experience varying levels of efficacy or adverse reactions to the same medication.Variability in drug...
110
Microbial Fermentation01:23

Microbial Fermentation

1.8K
Fermentation is a crucial anaerobic metabolic process that enables microbes to derive energy from sugar without relying on oxygen or an electron transport chain. This process is fundamental to various biological and industrial applications and is classified based on the metabolic products generated.Role of Pyruvate in FermentationPyruvate and its derivatives serve as key electron acceptors in fermentative pathways. The oxidation of NADH to regenerate NAD+ is essential for the continuation of...
1.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Application of machine learning to predict bronchiolitis severity in children: a single-centre retrospective cohort study.

European journal of pediatrics·2026
Same author

Metabolomics Profiling and In Vitro Genoprotective Effect of <i>Actinidia chinensis</i> Planch. var. <i>deliciosa</i> (A.Chev.) A.Chev. Leaf Extract.

Toxics·2026
Same author

Urinary Metabolomics and One-Class Classification To Discover Children Affected by Bile Acid Synthetic Disorders: A Case-Study.

Analytical chemistry·2026
Same author

Bioprospecting Italian biodiversity for identifying potential neuroprotective agents.

Scientific reports·2026
Same author

<i>Salvia pratensis</i> exhibits <i>in vitro</i> anti-cancer effects in triple-negative breast cancer through miR-34a-5p signaling.

Frontiers in nutrition·2026
Same author

Association Between the Dutch Mediterranean-Dietary Approaches to Stop Hypertension Intervention for Neurodegenerative Delay (MIND-NL) Diet Adherence and Systemic Tryptophan Metabolites in Older Adults at Risk of Cognitive Decline: An Exploratory Study.

Molecular nutrition & food research·2026

Related Experiment Video

Updated: Mar 13, 2026

The Terroir Concept Interpreted through Grape Berry Metabolomics and Transcriptomics
13:02

The Terroir Concept Interpreted through Grape Berry Metabolomics and Transcriptomics

Published on: October 5, 2016

11.0K

The Terroir Concept Interpreted through Grape Berry Metabolomics and Transcriptomics.

Silvia Dal Santo1, Mauro Commisso1, Erica D'Incà1

  • 1Biotechnology Department, University of Verona.

Journal of Visualized Experiments : Jove
|October 22, 2016
PubMed
Summary

This study reveals how grapevine (Vitis vinifera) terroir signatures are detectable in berry metabolome and transcriptome. Multivariate analysis integrates these

More Related Videos

Author Spotlight: Exploring the Fermentation Microbiome Through Next-Generation Sequencing
07:34

Author Spotlight: Exploring the Fermentation Microbiome Through Next-Generation Sequencing

Published on: December 1, 2023

1.3K
Comprehensive Workflow for the Genome-wide Identification and Expression Meta-analysis of the ATL E3 Ubiquitin Ligase Gene Family in Grapevine
10:40

Comprehensive Workflow for the Genome-wide Identification and Expression Meta-analysis of the ATL E3 Ubiquitin Ligase Gene Family in Grapevine

Published on: December 22, 2017

11.0K

Related Experiment Videos

Last Updated: Mar 13, 2026

The Terroir Concept Interpreted through Grape Berry Metabolomics and Transcriptomics
13:02

The Terroir Concept Interpreted through Grape Berry Metabolomics and Transcriptomics

Published on: October 5, 2016

11.0K
Author Spotlight: Exploring the Fermentation Microbiome Through Next-Generation Sequencing
07:34

Author Spotlight: Exploring the Fermentation Microbiome Through Next-Generation Sequencing

Published on: December 1, 2023

1.3K
Comprehensive Workflow for the Genome-wide Identification and Expression Meta-analysis of the ATL E3 Ubiquitin Ligase Gene Family in Grapevine
10:40

Comprehensive Workflow for the Genome-wide Identification and Expression Meta-analysis of the ATL E3 Ubiquitin Ligase Gene Family in Grapevine

Published on: December 22, 2017

11.0K

Area of Science:

  • Agricultural Science
  • Plant Biology
  • Biochemistry

Background:

  • Terroir significantly influences grapevine (Vitis vinifera) crop characteristics.
  • Understanding terroir's impact is crucial for viticulture and oenology.
  • Environmental factors and management practices shape grapevine traits.

Purpose of the Study:

  • To detect and analyze terroir signatures within the grapevine berry metabolome and transcriptome.
  • To demonstrate the utility of multivariate statistical analysis in identifying terroir-specific variations.
  • To integrate metabolomic and transcriptomic data for a comprehensive understanding of terroir effects.

Main Methods:

  • Utilized an untargeted LC-MS metabolomics approach for high-sensitivity metabolite profiling.
  • Employed MZmine software and fragmentation tree analysis for efficient data processing and metabolite identification.
  • Conducted comprehensive transcriptome analysis using microarrays covering nearly all predicted grapevine genes.
  • Implemented multivariate data analysis, including projection methods, to integrate and analyze diverse datasets.
  • Selected a specific clone of the Corvina cultivar and sampled across diverse macro-zones and growing seasons to minimize confounding variables.

Main Results:

  • Successfully detected distinct terroir signatures in the metabolome and transcriptome of Corvina grapevine berries.
  • Multivariate statistical analysis effectively identified correlations between environmental factors and molecular profiles.
  • The vintage-specific effect was successfully managed, allowing for detailed analysis of terroir influences.
  • Integrated metabolomic and transcriptomic data revealed informative correlations related to specific terroirs.

Conclusions:

  • Terroir signatures are demonstrably present and detectable in grapevine berry metabolomic and transcriptomic profiles.
  • Multivariate statistical analysis is a powerful tool for dissecting complex terroir-driven variations in Vitis vinifera.
  • The integrated approach provides a robust framework for understanding how environmental factors shape grapevine molecular composition.