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Updated: Mar 13, 2026

Multi-analyte Biochip MAB Based on All-solid-state Ion-selective Electrodes ASSISE for Physiological Research
Published on: April 18, 2013
Solid contact ion sensor with conducting polymer layer copolymerized with the ion-selective membrane for
Natalia Abramova1, Javier Moral-Vico2, Jordi Soley3
1BioMEMS Group, Instituto de Microelectrónica de Barcelona, Centro Nacional de Microelectrónica (CSIC), Campus U.A.B., 08193, Bellaterra, Barcelona, Spain; Lab. Artificial Sensors Syst., ITMO University, Kronverskiy pr. 49, 197101, St. Petersburg, Russia.
Abstract:
A new solid contact ion selective electrode with intermediate conducting polymer (CP) layer formed by electropolymerization on a gold electrode of a bifunctional monomer, n-phenyl-ethylenediamine-methacrylamide (NPEDMA), which contains a methacrylamide group attached to aniline, is presented. The conducting polymer was studied by means of optical spectroscopy, cyclic voltammetry and potentiometric measurements. Ca2+-ion-selective membrane based on acrylated urethane polymer was shown to co-polymerize with the CP forming highly adhesive boundary that prevents formation of water layers between the CP and membrane, thus enhancing the stability and life-time of the sensor. The designed ion-selective electrode was successfully used for determination of total calcium ion concentration in blood serum samples.

