A fast-responsive fluorescent probe based on BODIPY dye for sensitive detection of hypochlorite and its application...

Hypochlorite serves as a powerful antimicrobial agent in human immune system, the detection of which is of great significance. Herein a novel fluorescent probe based on BODIPY dye and diaminomaleonitrile has been synthesized and characterized to sense hypochlorite. The fluorescence of the system is dramatically enhanced by ClO^- due to the removal of C=N isomerization effect in physiological pH condition. The complete reaction only needs a few seconds, which enables the probe to facilitate real-time detection. This probe also has satisfactory selectivity for ClO^- even in the presence of other interferential ions and shows high sensitivity with a detection limit of 19.8nM. Furthermore, Probe 1 has been successfully applied to detect ClO^- in real water samples.