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Updated: Mar 13, 2026
Optic Nerve Transection: A Model of Adult Neuron Apoptosis in the Central Nervous System
Published on: May 12, 2011
Total recovery of optic nerve sheath meningioma
Pierre Charpentier1, Frederic Mouriaux2
1Centre Hospitalier Universitaire de Rennes, ille et Vilaine, Rennes, Catalunya, Girona, Spain.
Abstract:
We reported the case of a 43-year-old woman with a rapid progressive visual loss. The diagnosis of primary optic nerve sheath meningioma was made thanks to atypia evolution, clinical and radiological findings. The patient was treated with an intensity-modulated radiotherapy of 50.4 Gy in 28 fractions 2 months after the diagnosis. Visual acuity and visual field were completely recovered after 2 years of follow-up. No late side effects of irradiation were recorded.
Insights
A 43-year-old woman experienced rapid vision loss due to optic nerve sheath meningioma. Intensity-modulated radiotherapy led to complete visual recovery with no late side effects.
Area of Science:
- Ophthalmology
- Neurology
- Radiation Oncology
Background:
- Optic nerve sheath meningiomas (ONSMs) are rare tumors that can cause progressive visual loss.
- Early diagnosis and appropriate treatment are crucial for preserving vision.
Observation:
- A 43-year-old female presented with rapidly worsening vision.
- Clinical and radiological findings confirmed a primary optic nerve sheath meningioma.
Findings:
- The patient received intensity-modulated radiotherapy (IMRT) with a total dose of 50.4 Gy in 28 fractions.
- After a 2-year follow-up, complete recovery of visual acuity and visual field was observed.
Implications:
- IMRT is an effective treatment for optic nerve sheath meningioma, leading to significant visual recovery.
- This case highlights the potential for successful visual rehabilitation in patients with ONSM treated with radiotherapy, with no observed late adverse effects.
