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Published on: December 6, 2021
Efficient sonochemical green reaction of aldehyde, thiobarbituric acid and ammonium acetate using magnetically
1Department of Organic Chemistry, Faculty of Chemistry, University of Kashan, Kashan, 87317, Iran.
Abstract:
A facile one-pot and four-component economical synthesis of pyrido[2,3-d:6,5-d]dipyrimidines using aldehyde, 2-thiobarbituric acid and ammonium acetate in the presence of magnetically heterogeneous catalyst under ultrasonic irradiation in water is described. The present synthesis shows attractive characteristics such as; the use of magnetically recoverable and reusable catalyst, convenient one-pot operation, short reaction periods, high to excellent yields and the use of water as a green reaction medium, mild reaction conditions and is considered to be relatively environmentally benign.
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