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Updated: Mar 13, 2026

In Vivo Quantitative Assessment of Myocardial Structure, Function, Perfusion and Viability Using Cardiac Micro-computed Tomography
Published on: February 16, 2016
Role of PET-CT in the assessment of myocardial viability in patients with left ventricular dysfunction
Madhur Kumar Srivatsava1, M Indirani2, I Sathyamurthy3
1Consultant, Nuclear Medicine and PET-CT, Yashoda Hospital, Hyderabad, India.
Aim:
Role of PET-CT in assessment of myocardial viability in patients with LV dysfunction.
Methods:
This prospective study included 120 patients with LV dysfunction who underwent 99mTechnetium-Sestamibi myocardial perfusion SPECT-CT and 18FFDG cardiac PET-CT. They also underwent serial echocardiography and coronary angiography along with myocardial perfusion and FDG PET study.
Results:
Thirty-three patients had single vessel disease, 48 had triple vessel disease, and rest had double vessel disease. Among 786 segments, matched defects were seen in 432 (55%) and mismatched defects in 354 (45%) segments. 78 patients were surgically managed, and 42 were medically managed. The change in LVEF after surgical management was statistically significant compared to medical management.
Conclusion:
Viability assessment should be performed in patients who present after 12h of acute myocardial infarction or with LV dysfunction due to ischemic heart disease to decide upon appropriate surgical management.
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