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Related Concept Videos

Proteomics01:33

Proteomics

10.0K
A proteome is the entire set of proteins that a cell type produces. We can study proteomes using the knowledge of genomes because genes code for mRNAs, and the mRNAs encode proteins. Although mRNA analysis is a step in the right direction, not all mRNAs are translated into proteins.
Proteomics is the study of proteomes' function. It involves the large-scale systematic study of the proteome to denote the protein complement expressed by a genome. Scientist Mark Wilkins coined the term...
10.0K

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Resource: Mapping the Triticum aestivum proteome.

Owen Duncan1, Josua Trösch1, Ricarda Fenske1

  • 1ARC Centre of Excellence in Plant Energy Biology, University of Western Australia, Bayliss Building M316, Crawley, WA, 6009, Australia.

The Plant Journal : for Cell and Molecular Biology
|October 25, 2016
PubMed
Summary

Researchers mapped the wheat proteome across 24 samples, identifying tissue-specific proteins and 202 new transcripts. This resource aids understanding of bread wheat (Triticum aestivum) growth and grain production.

Keywords:
Triticum aestivumcell metabolismdatabaseproteomicswheatwheat genome

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Area of Science:

  • Plant biology
  • Proteomics
  • Genomics

Background:

  • Improving bread wheat (Triticum aestivum) yield and quality is crucial for global food security.
  • Understanding the wheat proteome is key to elucidating plant growth, development, and grain production.

Purpose of the Study:

  • To create a comprehensive, publicly accessible proteome map of wheat.
  • To identify tissue-specific sub-proteomes and ubiquitous protein markers.
  • To provide a resource for understanding wheat protein function and improving crop performance.

Main Methods:

  • Large-scale proteomic analysis of 24 wheat organ and developmental samples.
  • Proteogenomic mapping to identify novel protein-coding transcripts.
  • Hierarchical assessment of protein functional classes and their tissue distribution.

Main Results:

  • A publicly accessible wheat proteome map detailing 24 organ and developmental samples.
  • Identification of tissue-specific sub-proteomes and ubiquitous protein markers.
  • Discovery of 202 new protein-coding transcripts through proteogenomic mapping.

Conclusions:

  • The wheat proteome map provides a foundational resource for plant science research.
  • This study enhances our understanding of wheat organ development and protein dynamics.
  • The interactive database (www.wheatproteome.org) facilitates targeted proteomic assays and functional studies.