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Related Concept Videos

Patch Clamp01:18

Patch Clamp

Many fundamental cell functions such as muscle contraction and nerve transmission rely on the electrical signals produced by the movement of positively and negatively charged ions across the cell membrane. One competent method to record current flowing across the whole cell or single ion channel is the patch-clamp technique.
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Principles Of Column Chromatography01:13

Principles Of Column Chromatography

The chromatography technique was first invented in 1901 by Michael S. Tswett, a Russian botanist, to separate plant pigments using organic solvents. Further, in 1941, Archer John Porter Martin and R. L. M. Synge modified the technique by packing silica gel into a column. A mixture of amino acids was then separated on the packed column using chloroform and water mixture as the mobile phase. This was the first report on column chromatography. At present, column chromatography is a widely used...
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Related Experiment Video

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Fabrication and Visualization of Capillary Bridges in Slit Pore Geometry
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Capillary Bridging as a Tool for Assembling Discrete Clusters of Patchy Particles.

Bhuvnesh Bharti1,2, David Rutkowski1, Koohee Han1

  • 1Department of Chemical and Biomolecular Engineering, North Carolina State University , Raleigh, North Carolina 27695, United States.

Journal of the American Chemical Society
|October 25, 2016
PubMed
Summary

Lipid-induced capillary bridging assembles patchy particles into ordered clusters. Temperature-controlled phase transitions enable tunable assembly and disassembly of these colloidal structures.

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Area of Science:

  • Colloid and Surface Science
  • Materials Science
  • Soft Matter Physics

Background:

  • Janus and patchy particles are key for studying directed assembly and creating novel materials.
  • Understanding self-assembly mechanisms is crucial for designing advanced colloidal structures.

Purpose of the Study:

  • To introduce lipid-induced capillary bridging as a novel method for assembling patchy particles.
  • To investigate the role of lipid phase transitions in controlling particle assembly and disassembly.
  • To determine how particle patch characteristics influence equilibrium cluster morphology.

Main Methods:

  • Selective wetting of iron oxide patches on latex microspheres with liquid lipid.
  • Formation of interparticle capillary bridges to drive cluster assembly.
  • Utilizing temperature-driven phase transitions of fatty acids for assembly control.
  • Complementary Monte Carlo simulations to analyze equilibrium cluster morphology.

Main Results:

  • Lipid capillary bridges successfully assembled patchy particles into 2D and 3D clusters.
  • Liquid bridge phase allowed particle reorganization and equilibrium configuration formation.
  • Fatty acid phase transitions acted as a thermal switch for reversible cluster assembly/disassembly.
  • Simulations confirmed that patch size, number, and shape dictate equilibrium cluster morphology.

Conclusions:

  • Lipid-induced capillary bridging is a versatile and robust method for assembling thermoresponsive colloidal clusters.
  • The approach is generic and adaptable for various particle shapes and surface chemistries.
  • This technique enables the creation of sophisticated colloidal molecules with tunable properties.