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Related Experiment Videos

[Experimental studies on shock-wave cholelithotripsy].

W Golder

    Helvetica Chirurgica Acta
    |June 1, 1989
    PubMed
    Summary
    This summary is machine-generated.

    Extracorporeal shock-wave lithotripsy for gallstones showed partial disintegration and lung hemorrhages in pigs. Combining shock-wave lithotripsy with MTBE-litholysis improved results, suggesting specific patient positioning for human treatment.

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    Area of Science:

    • Biomedical Engineering
    • Gastroenterology
    • Nephrology

    Context:

    • Gallstone disease is a common condition requiring effective treatment.
    • Extracorporeal shock-wave lithotripsy (ESWL) is a non-invasive treatment option.
    • Previous ESWL devices have limitations in efficacy and safety.

    Purpose:

    • To evaluate an experimental electromagnetic shock-wave device for gallstone fragmentation.
    • To assess the safety and efficacy of this device in an in vivo animal model.
    • To determine optimal treatment parameters and patient positioning for human application.

    Summary:

    • An experimental electromagnetic shock-wave lithotripsy device was tested on 45 calculi in pigs, including human gallstones.
    • Partial disintegration of gallstones was observed, with improved results when combined with MTBE-litholysis.

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  • The primary complication was extensive lung hemorrhage, suggesting anatomical differences may mitigate this risk in humans.

    • Impact:

    • Findings suggest potential for ESWL in gallstone management, with modifications for safety.
    • Recommendations include prone positioning and deep inspiration during treatment for human patients.
    • Optimal parameters involve a maximum of 2,000 shock waves at 18-20 kV per session.