Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Irradiation synchronized with respiration gate.

K Ohara1, T Okumura, M Akisada

  • 1Department of Radiology, University Hospital, University of Tsukuba, Japan.

International Journal of Radiation Oncology, Biology, Physics
|October 1, 1989
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

MR Imaging Findings of Carcinoma Ex Pleomorphic Adenoma Related to Extracapsular Invasion and Prognosis.

AJNR. American journal of neuroradiology·2022
Same author

Anxiety relaxation during MRI with a patient-friendly audiovisual system.

Radiography (London, England : 1995)·2022
Same author

Prognostic Factors of Stroke-Like Migraine Attacks after Radiation Therapy (SMART) Syndrome.

AJNR. American journal of neuroradiology·2022
Same author

An Investigation of Water Diffusivity Changes along the Perivascular Space in Elderly Subjects with Hypertension.

AJNR. American journal of neuroradiology·2021
Same author

Selective Motor Control is a Clinical Correlate of Brain Motor Tract Impairment in Children with Spastic Bilateral Cerebral Palsy.

AJNR. American journal of neuroradiology·2021
Same author

Lumbosacral subdural hematoma associated with cranial subdural hematoma and craniocerebral surgery: Three cases and a systemic literature review.

Neuro-Chirurgie·2021

This study introduces respiratory gating for lung cancer radiotherapy, enabling precise tumor targeting during breathing. The technique ensures accurate radiation delivery for tumors near the diaphragm.

Area of Science:

  • Radiation Oncology
  • Medical Physics
  • Pulmonology

Background:

  • Tumors in the thoracic region, particularly lung tumors, often exhibit movement due to respiration.
  • This respiratory-induced motion complicates radiotherapy, potentially reducing treatment accuracy and increasing dose to surrounding healthy tissues.
  • Precise targeting is crucial for effective treatment, especially for tumors located near critical structures like the diaphragm.

Purpose of the Study:

  • To develop and evaluate a respiratory gating technique for radiotherapy of tumors affected by breathing motion.
  • To improve the accuracy and efficacy of radiation treatment for lung tumors.
  • To assess the feasibility of real-time tumor motion management during radiation delivery.

Main Methods:

  • Developed a respiratory gating system using a linear accelerator's microwave oscillator synchronized with respiratory cycle signals.

Related Experiment Videos

  • Validated the technique using a lung cancer phantom and in clinical trials with seven lung tumor patients.
  • Employed a mask for ventilation monitoring in the phantom and airbags for thoracoabdominal pressure measurement in patients and the phantom to track tumor excursion.
  • Utilized low-sensitivity film for treatment verification.

    • Main Results:

    • The respiratory gating technique successfully controlled irradiation timing based on specific points in the respiratory cycle.
    • Tumor excursion was effectively detected using the implemented monitoring systems.
    • Treatment verification using low-sensitivity film confirmed the efficacy of the gating method.
    • The technique demonstrated its ability to ensure more precise radiotherapy delivery.

    Conclusions:

    • Respiratory gating is an effective method for managing tumor motion caused by breathing during radiotherapy.
    • This technique significantly enhances the precision of radiation delivery for tumors, especially those located near the diaphragm.
    • The developed system offers a viable solution for improving radiotherapy outcomes in patients with mobile thoracic tumors.