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Related Concept Videos

Mitral Regurgitation I: Introduction01:20

Mitral Regurgitation I: Introduction

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Mitral regurgitation is characterized by the backward circulation of blood from the left ventricle to the left atrium during systole, a phase of the cardiac cycle when the heart contracts and pumps blood out of the chambers. This abnormal flow occurs primarily due to the dysfunction of the mitral valve or its supporting structures, which include the mitral leaflets, chordae tendineae, annulus, and papillary muscles.Etiology and Mechanisms:Primary Mitral Regurgitation: This type arises from...
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Mitral Stenosis I: Introduction01:22

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Mitral Valve Stenosis (MVS) is a heart condition where the mitral valve narrows, impeding blood circulation from the left atrium to the left ventricle. The etiology and pathophysiology of this condition are multifaceted, leading to a cascade of cardiovascular complications.Causes of Mitral Valve StenosisRheumatic Heart Disease: It is the main cause of mitral valve stenosis, particularly in developing nations. This condition arises from rheumatic fever, an inflammatory illness resulting from...
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Cardiomyopathy IV: Restrictive Cardiomyopathy01:29

Cardiomyopathy IV: Restrictive Cardiomyopathy

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Restrictive cardiomyopathy (RCM) is a rare heart muscle disease characterized by impaired ventricular filling due to stiffened ventricular walls, leading to significant diastolic dysfunction.EtiologyRestrictive cardiomyopathy can arise from both inherited and acquired diseases, many of which are systemic. It is categorized into four main types: infiltrative, storage, non-infiltrative, and endomyocardial diseases.Infiltrative diseases, such as amyloidosis, lead to RCM by depositing amyloid...
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Cardiomyopathy III: Hypertrophic Cardiomyopathy01:29

Cardiomyopathy III: Hypertrophic Cardiomyopathy

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Hypertrophic cardiomyopathy, or HCM, is an autosomal dominant genetic disorder characterized by asymmetric left ventricular hypertrophy without ventricular dilation. It is more common in men and is typically diagnosed in young, athletic adults.EtiologyHCM is primarily genetic and is caused by mutations in genes encoding sarcomeric proteins. Researchers have identified over 1400 mutations across at least 11 different genes. Among these, the most frequently occurring mutations are found in the...
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Cardiac Catheterization II: Right Heart Catheterization01:21

Cardiac Catheterization II: Right Heart Catheterization

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Right Heart Catheterization: An OverviewRight heart catheterization is an invasive diagnostic procedure that measures right-sided cardiac and pulmonary artery pressures, calculates cardiac output, and identifies intracardiac shunts. It provides detailed hemodynamic data essential for diagnosing and managing various cardiovascular conditions, such as pulmonary hypertension.Access SitesCommon access sites for right heart catheterization include the internal jugular vein in the neck region, the...
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Related Experiment Video

Updated: Mar 13, 2026

Chronic Thromboembolic Pulmonary Hypertension and Assessment of Right Ventricular Function in the Piglet
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Ewing Sarcoma in the Right Ventricle.

Marija Petrovic, Bihong Zhao, Manoj Thangam

    Texas Heart Institute Journal
    |October 26, 2016
    PubMed
    Summary

    This case study details a rare instance of Ewing sarcoma (a bone cancer) metastasizing to the heart's right ventricle. Surgical resection was successful, with no recurrence observed a year later.

    Keywords:
    Heart neoplasms/secondary/surgeryheart ventricles/surgeryneoplasm invasivenessoncogene proteins, fusionsarcoma, Ewing/genetics/pathology/surgerytreatment outcome

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    Area of Science:

    • Oncology
    • Cardiology
    • Pathology

    Background:

    • Ewing sarcoma is a rare primary bone cancer.
    • Cardiac metastases are uncommon, especially from Ewing sarcoma.
    • This study focuses on a unique case of right ventricular metastasis.

    Observation:

    • A 36-year-old male presented with an asymptomatic, pedunculated right ventricular cardiac tumor.
    • The patient had a prior diagnosis of translocation-negative Ewing sarcoma treated with chemotherapy and amputation.
    • Surgical resection of the cardiac mass was performed.

    Findings:

    • Histopathological analysis confirmed the cardiac tumor as metastatic Ewing sarcoma.
    • Post-operative echocardiograms revealed normal biventricular size and function.
    • The patient remained disease-free one year after surgery, with no sarcoma recurrence.

    Implications:

    • This case highlights the possibility of Ewing sarcoma metastasis to the heart.
    • It underscores the importance of considering rare metastatic sites in cancer patients.
    • Successful surgical management of cardiac metastases can lead to favorable outcomes.