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Related Concept Videos

Appendicitis-II: Diagnostic Studies and Management01:29

Appendicitis-II: Diagnostic Studies and Management

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Diagnosing and managing appendicitis requires a structured and comprehensive approach that spans from initial assessment to postoperative care. Here is an overview of the process:
Diagnosing Appendicitis
It requires a multifaceted approach, starting with a detailed physical examination to pinpoint the location and nature of the pain and identify any associated symptoms. Laboratory tests play a crucial role. A complete Blood Count (CBC) typically reveals leukocytosis (an increased number of...
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Appendicitis-I: Introduction01:22

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The appendix, a small, narrow, blind tube extending from the inferior part of the cecum, is widely regarded as a vestigial organ, having lost much of its original function through evolution. Despite its diminished role, the appendix can become inflamed, a condition known as appendicitis.
Etiology: Appendicitis can arise from various causes, primarily rooted in the obstruction of the appendix lumen. Factors contributing to this obstruction include fecal accumulation, lymphoid hyperplasia and, in...
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Negative Appendectomy: Clinical and Economic Implications.

Yang Lu1, Scott Friedlander, Steven L Lee

  • 1Los Angeles Biomedical Research Institute, Torrance, California, USA.

The American Surgeon
|October 26, 2016
PubMed
Summary
This summary is machine-generated.

Negative appendectomy (NA) is performed less often but increases hospital costs and patient morbidity. This study found NA does not reduce perforated appendicitis rates, challenging historical justifications.

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Area of Science:

  • Surgical outcomes research
  • Health services research

Background:

  • Historically, negative appendectomy (NA) was performed to prevent appendiceal perforation.
  • NA was believed to have minimal morbidity and cost implications.

Purpose of the Study:

  • To evaluate the frequency, clinical characteristics, and economic impact of NA.
  • To determine if NA influences rates of perforated appendicitis.

Main Methods:

  • Retrospective review of 274,405 inpatient admissions for nonincidental appendectomy in California (2005-2011).
  • Analysis of NA rates, patient demographics, length of stay, cost, and morbidity.
  • Multivariate regression to identify factors associated with NA.

Main Results:

  • NA rates decreased from 4.2% to 2.5% (2005-2011).
  • NA was associated with longer hospital stays, higher costs ($8626 vs $7605), and increased morbidity (4.7% vs 1.9%) compared to nonperforated appendicitis.
  • Female gender, African American race, and public insurance were linked to higher NA rates.

Conclusions:

  • NA is associated with significant clinical and financial burdens.
  • NA does not appear to reduce the incidence of perforated appendicitis.
  • The traditional justification for NA is not supported by current data.