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Surveying Low-Cost Methods to Measure Lifespan and Healthspan in Caenorhabditis elegans
Published on: May 18, 2022
Heat FLiPs a Hormonal Switch for Longevity
Murat Artan1, Seon Woo A An1, Seung-Jae V Lee2
1Department of Life Sciences, Pohang University of Science and Technology, Pohang, Gyeongbuk, South Korea.
Abstract:
Temperature-sensing neurons in C. elegans reduce the life-shortening effects of high temperatures via steroid signaling. In this issue of Developmental Cell, Chen et al. (2016) elucidate the underlying mechanisms by which the transcription factor CREB induces the neuropeptide FLP-6 in the temperature-sensing neurons to counteract the life-shortening effects of high temperature.
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