Related Experiment Video
Updated: Mar 13, 2026

Real-Time Fluorescent Measurement of Synaptic Functions in Models of Amyotrophic Lateral Sclerosis
Published on: July 16, 2021
Axonal Degeneration: RIPK1 Multitasking in ALS
Kristin Politi1, Serge Przedborski2
1Departments of Pathology & Cell Biology, Columbia University Medical Center, 630 West 168(th) Street, New York, NY 10032, USA; The Center for Motor Neuron Biology and Disease, Columbia University Medical Center, 630 West 168(th) Street, New York, NY 10032, USA.
Abstract:
A recent study reports that microglia and oligodendrocytes promote motor neuron degeneration by inducing inflammation and necroptosis in a manner dependent on receptor-interacting kinase 1 (RIPK1). These findings could be significant for our understanding of the neurobiology and treatment of neurodegenerative diseases like amyotrophic lateral sclerosis.
More Related Videos
07:14Optogenetic Phase Transition of TDP-43 in Spinal Motor Neurons of Zebrafish Larvae
Published on: February 25, 2022
10:10Use of Two Dimensional Semi-denaturing Detergent Agarose Gel Electrophoresis to Confirm Size Heterogeneity of Amyloid or Amyloid-like Fibers
Published on: April 26, 2018