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What Role Does Allergy Play in Chronic Ear Disease and Laryngitis?
Michael P Platt1, Christopher D Brook2, Jacob Kuperstock1
1Department of Otolaryngology- Head and Neck Surgery, Boston University School of Medicine, 820 Harrison Avenue, Boston, MA, 02118, USA.
Abstract:
IgE-mediated allergy plays a well-established role in both nasal and pulmonary diseases due to the common epithelium and shared mediator responses of the upper and lower airways. This "unified airway" concept has also been described in other sites within the head and neck that contain similar respiratory mucosa: the middle ear and the larynx. This review will highlight the data suggesting a role for IgE-mediated allergic disease in chronic laryngopharyngeal and middle ear disease and the role for allergy testing to aid in diagnosis and treatment of these disorders.
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