Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Stem Cell Therapy for Tissue Regeneration01:21

Stem Cell Therapy for Tissue Regeneration

4.8K
Stem cell therapy is a method used in regenerative medicine to repair and restore function to damaged tissues and organs. Stem cells have the potential to proliferate and differentiate into various tissue types, making them ideal candidates for tissue regeneration. For example, hematopoietic stem cell transplants are commonly used in blood cancer treatment to replenish damaged bone marrow and restore healthy blood cells.
Types of Stem Cells used in Stem Cell Therapy
The two main cell...
4.8K
Stem Cell Culture01:17

Stem Cell Culture

6.4K
Stem cell research aims to find ways to use stem cells to regenerate and repair cellular damage. Over time, most adult cells undergo the wear and tear of aging and lose their ability to divide and repair themselves. Stem cells do not display a particular morphology or function. Adult stem cells, which exist as a small subset of cells in most tissues, keep dividing and can differentiate into a number of specialized cells generally formed by that tissue. These cells enable the body to renew and...
6.4K
Adult Stem Cells01:33

Adult Stem Cells

34.1K
Stem cells are undifferentiated cells that divide and produce more stem cells or progenitor cells that differentiate into mature, specialized cell types. All the cells in the body are generated from stem cells in the early embryo, but small populations of stem cells are also present in many adult tissues including the bone marrow, brain, skin, and gut. These adult stem cells typically produce the various cell types found in that tissue—to replace cells that are damaged or to continuously...
34.1K
Embryonic Stem Cells00:58

Embryonic Stem Cells

33.1K
Embryonic stem (ES) cells are undifferentiated pluripotent cells, meaning they can produce any cell type in the body. This gives them tremendous potential in science and medicine since they can generate specific cell types for use in research or to replace body cells lost due to damage or disease.
33.1K
Embryonic Stem Cells00:57

Embryonic Stem Cells

5.7K
Embryonic stem (ES) cells were first discovered in mice in 1981 by Martin Evans. In 1998, James Thomson identified a method to isolate embryonic stem cells from humans. Human embryonic stem cells (hESCs) are obtained from 3-5 day old embryos that remain unused after an in vitro fertilization procedure.
ES cells are grown in a culture medium where they can divide indefinitely, creating ES cell lines. Under certain conditions, ES cells can differentiate, either spontaneously into a variety of...
5.7K
iPS Cell Differentiation01:22

iPS Cell Differentiation

3.2K
The ability of induced pluripotent stem cells or iPSCs to differentiate into most body cell types has stimulated repair and regenerative medicine research over the past few decades. iPSC-derived blood cells, hepatocytes, beta islet cells, cardiomyocytes, neurons, and other cell types can repair injuries or regenerate damaged tissue in diseases such as diabetes and neurodegenerative disorders.
3.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Incidence and impact of pseudoprogression and mixed responses in metastatic renal cell carcinoma patients treated with ipilimumab/nivolumab: a retrospective analysis.

Acta oncologica (Stockholm, Sweden)·2026
Same author

European Association of Urology and American Society of Clinical Oncology Guidelines on Penile Cancer: A Summary of the 2026 Guidelines Update.

European urology·2026
Same author

Prognostic and Predictive Value of the Clearseq1-4 Tumor Microenvironment Classification in Localized and Metastatic Clear-Cell Renal Cell Carcinoma.

Cancer research communications·2026
Same author

Effectiveness of preoperative chemotherapy and radical cystectomy in clinically node-positive and node-negative bladder cancer patients.

World journal of urology·2026
Same author

Testicular Seminoma After Testicular Torsion Presenting With a Contralateral Inguinal Lymph Node Metastasis: A Case Report and Literature Review.

Cureus·2026
Same author

Re: Blackmur JP, Rossi SH, Kuusk T, et al. Prediction Models for Shared Decision-making by Patients with Localised Renal Masses: A Systematic Review and a Survey of Patient and Clinician Priorities. Eur Urol Oncol. In press. http://dx.doi.org/10.1016/j.euo.2026.02.008: Outcome Prediction in Localised Renal Cancer: We Need to Do Better.

European urology oncology·2026

Related Experiment Video

Updated: Mar 13, 2026

Isolation of Adipose Derived Regenerative Cells for the Treatment of Erectile Dysfunction Following Radical Prostatectomy
09:49

Isolation of Adipose Derived Regenerative Cells for the Treatment of Erectile Dysfunction Following Radical Prostatectomy

Published on: December 28, 2021

4.0K

Stem Cell Therapy for Erectile Dysfunction: Progress and Future Directions.

Maarten Albersen1, Emmanuel Weyne1, Trinity J Bivalacqua2

  • 1Laboratory for Experimental Urology, Gene and Stem Cells Applications, Department of Development and Regeneration, University of Leuven, Leuven, Belgium.

Sexual Medicine Reviews
|May 1, 2013
PubMed
Summary
This summary is machine-generated.

Stem cell therapy shows promise for treating erectile dysfunction (ED) by addressing underlying causes, not just symptoms. Further research and clinical trials are needed to establish its role in restoring penile function.

Keywords:
Adipose Tissue‐Derived Stem CellsAgingBone Marrow‐Derived Stem CellsCavernous Nerve InjuryDiabetesErectile DysfunctionPeyronie's DiseaseRegenerative MedicineStromal Vascular Fraction

More Related Videos

Embryonic Stem Cell-Derived Endothelial Cells for Treatment of Hindlimb Ischemia
09:11

Embryonic Stem Cell-Derived Endothelial Cells for Treatment of Hindlimb Ischemia

Published on: January 23, 2009

12.3K
Treatment Model for Young Patients with Psychogenic Erectile Dysfunction and Resultant Infertility
04:22

Treatment Model for Young Patients with Psychogenic Erectile Dysfunction and Resultant Infertility

Published on: May 30, 2025

1.2K

Related Experiment Videos

Last Updated: Mar 13, 2026

Isolation of Adipose Derived Regenerative Cells for the Treatment of Erectile Dysfunction Following Radical Prostatectomy
09:49

Isolation of Adipose Derived Regenerative Cells for the Treatment of Erectile Dysfunction Following Radical Prostatectomy

Published on: December 28, 2021

4.0K
Embryonic Stem Cell-Derived Endothelial Cells for Treatment of Hindlimb Ischemia
09:11

Embryonic Stem Cell-Derived Endothelial Cells for Treatment of Hindlimb Ischemia

Published on: January 23, 2009

12.3K
Treatment Model for Young Patients with Psychogenic Erectile Dysfunction and Resultant Infertility
04:22

Treatment Model for Young Patients with Psychogenic Erectile Dysfunction and Resultant Infertility

Published on: May 30, 2025

1.2K

Area of Science:

  • Regenerative Medicine
  • Urology
  • Stem Cell Biology

Background:

  • Erectile dysfunction (ED) is a prevalent condition often managed with temporary solutions.
  • Current ED treatments focus on symptom relief rather than addressing root causes.
  • Stem cell therapy offers a potential approach to reverse pathophysiological changes contributing to ED.

Approach:

  • A nonsystematic literature review was conducted.
  • Searched major scientific databases (PubMed, Scopus, SciVerse, Google Scholar) for English literature from 1966-2013.
  • Focused on preclinical and clinical evidence of stem cell application for ED treatment.

Key Points:

  • Preclinical studies demonstrate beneficial effects of stem cell therapy in various ED models (nerve injury, Peyronie's disease, diabetes, aging, hyperlipidemia).
  • Mechanisms of action are evolving, with a shift from cell engraftment/differentiation towards paracrine effects.
  • Limited clinical data exists, with one study in diabetic patients and ongoing trials.

Conclusions:

  • Stem cell therapy is an emerging field for erectile dysfunction (ED) treatment.
  • Restoring penile vascular and neuronal homeostasis is a key focus.
  • Extensive basic research and diverse human trials are necessary to define stem cell therapy's role in ED.