Residual stromal bed thickness correlates with regression of myopia after LASIK

The purpose of this study was to evaluate the correlation between residual stromal bed thickness (hereinafter bed thickness) and regression of myopia after LASIK, taking into consideration the long-term outcomes.

A total of 177 patients (309 eyes) and 41 patients (70 eyes) were retrospectively reviewed at 5 and 10 years after surgery, respectively. These patients were also continuously examined throughout the study. All patients underwent laser in situ keratomileusis (LASIK) for myopia in our clinic and scored at least 1.0 (0 logMAR) uncorrected distance visual acuity (UCVA) 1 month after surgery. Bonferroni-Dunn method and Student's t-test were used for statistical analyses.

Cases with a refractive value (spherical equivalent) of less than -6.0 D (Group A) were compared to those with -6.1 D or higher (Group B). There was a statistically significant decrease in Group B UCVA of 0.04 logMAR and 0.12 logMAR at 5 and 10 years after surgery, respectively. With regard to the relationship between regression of myopia and bed thickness in the long-term, there was a significantly higher frequency of regression of myopia in cases with less than 350 μm bed thickness compared to those with 350 μm and more, in a surgical volume of more than -6.1 D (Group B).

The present study indicates that bed thickness correlates with regression of myopia after LASIK and enough bed thickness is important to maintain good UCVA in the long-term.