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Methotrexate hypersensitivity reactions in pediatrics: Evaluation and management

Meredith A Dilley1,2, Joyce P Lee1, Ana Dioun Broyles1,2

  • 1Division of Immunology at Boston Children's Hospital, Boston, Massachusetts.

Pediatric Blood & Cancer
|October 28, 2016
PubMed
Summary

Hypersensitivity reactions to methotrexate (MTX) are rare. This study found skin testing, graded challenge, and desensitization safe and effective for evaluating and managing pediatric patients with MTX hypersensitivity.

Keywords:
chemotherapydesensitizationdrug allergymethotrexate

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