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Published on: June 30, 2018
Oropouche virus is detected in peripheral blood leukocytes from patients
Luciano Kleber de Souza Luna1, Alcir Humberto Rodrigues1, Rodrigo Ivo Marques Santos1
1Department of Cell and Molecular Biology, Virology Research Center, Ribeirao Preto School of Medicine, University of Sao Paulo, Ribeirao Preto, São Paulo, Brazil.
Abstract:
Oropouche virus (OROV) is a frequent cause of arboviral febrile disease in the Amazon. The present report describes studies done in two patients, one of them; the first OROV human case acquired outside of the Amazon, which have revealed for the first time the presence of OROV in peripheral blood leukocytes. This novel finding raises important issues regarding pathogenesis of human infections and may offer a new tool, for the rapid diagnosis of this neglected infection. J. Med. Virol. 89:1108-1111, 2017. © 2017 Wiley Periodicals, Inc.
