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Updated: Mar 13, 2026

Genome-Wide Analysis of DNA Methylation in Gastrointestinal Cancer
Published on: September 18, 2020
Epigenetic biomarkers in colorectal cancer: premises and prospects
Mozhdeh Zamani1, Seyed Vahid Hosseini1, Pooneh Mokarram2,3
1a Colorectal Research Center , Shiraz University of Medical Sciences , Shiraz , IR Iran.
Context:
Colorectal cancer is one of the most common cancers worldwide. Epigenetic alterations play an important role in the pathogenesis of the colorectal cancer.
Objective:
This review has focused on the most recent investigations, which has suggested potential epigenetic biomarkers in colorectal cancer.
Methods:
Evidences were achieved by searching online medical databases including Google scholar, Pubmed, Scopus and Science Direct.
Results:
Extensive studies have indicated that aberrant epigenetic modifications could serve as potential biomarkers for diagnosis, prognosis and prediction of colorectal cancer.
Conclusion:
Advances in aberrant epigenetic modifications can open new avenues for exploration of reliable and robust biomarkers to improve the management of CRC patients.
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