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Related Concept Videos

Bone Marrow Sampling and Transplants01:22

Bone Marrow Sampling and Transplants

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Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy...
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Related Experiment Video

Updated: Mar 13, 2026

Comprehensive Protocol to Sample and Process Bone Marrow for Measuring Measurable Residual Disease and Leukemic Stem Cells in Acute Myeloid Leukemia
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Comprehensive Protocol to Sample and Process Bone Marrow for Measuring Measurable Residual Disease and Leukemic Stem Cells in Acute Myeloid Leukemia

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Performing a Better Bone Marrow Aspiration.

Mayo F Friedlis1, Christopher J Centeno2

  • 1Stem Cell Arts, 5550 Friendship Blvd, Chevy Chase, MD 20815, USA.

Physical Medicine and Rehabilitation Clinics of North America
|October 30, 2016
PubMed
Summary
This summary is machine-generated.

This study introduces an improved bone marrow aspiration (BMA) technique using imaging guidance and anesthesia to maximize mesenchymal stem cell yield for regenerative medicine. The method is well-tolerated and provides a high stem cell harvest.

Keywords:
Bone marrow aspirationBone marrow aspiration techniqueBone marrow stem cellsImage-guided bone marrow aspirationStem cells

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Area of Science:

  • Regenerative Medicine
  • Orthopedics
  • Stem Cell Biology

Background:

  • Bone marrow aspiration (BMA) is crucial for harvesting stem cells in regenerative medicine.
  • Optimizing mesenchymal stem cell yield is a key goal in interventional orthopedics.

Purpose of the Study:

  • To present an improved bone marrow aspiration method.
  • To maximize mesenchymal stem cell yield through guided aspiration.
  • To detail a technique that is well-tolerated by patients.

Main Methods:

  • Utilizing fluoroscope or ultrasound guidance for bone marrow aspiration.
  • Administering anesthesia during the aspiration procedure.
  • Providing a step-by-step guide for the improved BMA technique.

Main Results:

  • The improved BMA method achieves the highest possible stem cell yield.
  • The procedure is well-tolerated by patients.
  • Detailed procedural guides are provided for both ultrasound- and fluoroscope-guided BMA.

Conclusions:

  • Image-guided bone marrow aspiration with anesthesia is an effective method for maximizing stem cell yield.
  • This technique offers a well-tolerated approach for regenerative medicine applications.
  • The study provides practical guidance for implementing this improved BMA procedure.