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Author Spotlight: Development of a Smartphone-Enhanced Paper-Based Device for Rapid Dengue NS1 Detection
Published on: January 26, 2024
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[Autochthonous dengue].
F Sorge1, P Minodier2, N Velayudhan-Deschamps3
1Service de pédiatrie, hôpital Necker, 149, rue de Sèvres, 75015 Paris, France; Service de pédiatrie, hôpital Robert-Debré, 48, boulevard Sérurier, 75019 Paris, France.
Summary
Dengue, a mosquito-borne arboviral disease, poses an epidemic risk in France due to imported cases and local Aedes vector spread. Pediatricians must recognize and manage severe dengue, especially in young children.
Area of Science:
- Arbovirology
- Infectious Diseases
- Public Health
Background:
- Dengue virus (DENV) is a significant arboviral disease with increasing global prevalence.
- Autochthonous dengue transmission has been documented in metropolitan France since 2004.
- The Aedes vector mosquito's spread in France heightens the risk of dengue epidemics.
Purpose of the Study:
- To present the epidemiological, pathophysiological, clinical, diagnostic, and therapeutic characteristics of dengue.
- To prepare French pediatricians to manage dengue cases, including severe forms.
- To highlight the potential epidemic risk of dengue in metropolitan France.
Main Methods:
- Review of epidemiological data on dengue in France.
- Analysis of pathophysiological mechanisms of dengue infection.
- Compilation of clinical presentations, diagnostic methods, and therapeutic strategies for dengue.
Main Results:
- Dengue presents an emerging risk in continental France due to imported cases and vector proliferation.
- Severe dengue cases are infrequent but carry the highest lethality in children under five.
- Understanding dengue's multifaceted characteristics is crucial for effective management.
Conclusions:
- Metropolitan France faces a growing dengue epidemic risk.
- Pediatricians require specific knowledge for diagnosing and managing dengue, particularly severe forms.
- Timely recognition and management are essential to mitigate dengue's impact, especially in pediatric populations.
