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Related Concept Videos

CRISPR/Cas9 Genome Editing01:28

CRISPR/Cas9 Genome Editing

2.4K
The CRISPR-Cas system serves as a bacterial defense mechanism against invading genetic elements such as viruses and plasmids, forming the foundation for its adaptation as a powerful genome-editing tool. Originally discovered in prokaryotes, this system has been repurposed to revolutionize genetic engineering across a wide range of organisms, including plants, animals, and humans. The core component, Cas9, is an endonuclease derived from Streptococcus pyogenes, capable of introducing...
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Multiallelic, Targeted Mutagenesis of Magnesium Chelatase With CRISPR/Cas9 Provides a Rapidly Scorable Phenotype in Highly Polyploid Sugarcane.

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Gene Editing Technologies for Sugarcane Improvement: Opportunities and Limitations.

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Related Experiment Video

Updated: Mar 13, 2026

Author Spotlight: Streamlining Rice Breeding with CRISPR/Cas for Obtaining Optimal Phenotypic and Agronomic Traits
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Author Spotlight: Streamlining Rice Breeding with CRISPR/Cas for Obtaining Optimal Phenotypic and Agronomic Traits

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Genome Editing in Sugarcane: Challenges Ahead.

Chakravarthi Mohan1

  • 1Molecular Biology Laboratory, Department of Genetics and Evolution, Federal University of Sao Carlos Sao Carlos, Brazil.

Frontiers in Plant Science
|October 30, 2016
PubMed
Summary
This summary is machine-generated.

Genome editing, particularly CRISPR/Cas9, offers crop enhancement opportunities. While promising, its application in sugarcane is nascent, facing challenges like large genome size and low efficiency.

Keywords:
CRISPR/Cas9TALENsZFNsgenome editingpolyploidsugarcane

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Area of Science:

  • Agricultural Science
  • Biotechnology
  • Genetics

Background:

  • Genome editing tools like ZFNs and TALENs have been used for crop improvement.
  • The CRISPR/Cas9 system offers a more versatile and effective alternative for genome editing applications.
  • Sugarcane genome editing is in its early stages, with limited research available.

Approach:

  • Reviewing the current state of genome editing technologies in crop plants.
  • Highlighting the potential and challenges of applying CRISPR/Cas9 in sugarcane.
  • Discussing the first reported genome editing study in sugarcane for lignin reduction.

Key Points:

  • CRISPR/Cas9 is a powerful and versatile genome editing tool.
  • Successful genome editing has been achieved in several crop plants.
  • The first genome editing in sugarcane involved TALENs to reduce lignin content for biofuel production.

Conclusions:

  • Sugarcane genome editing faces significant challenges including large genome size, polyploidy, and low transformation efficiency.
  • Further research and development are needed to overcome these hurdles for widespread application.
  • Genome editing holds promise for improving sugarcane traits relevant to agriculture and biofuel production.