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Related Concept Videos

Extracorporeal Removal of Drugs: Hemoperfusion and Hemofiltration01:25

Extracorporeal Removal of Drugs: Hemoperfusion and Hemofiltration

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Hemoperfusion and hemofiltration are critical techniques in medical treatments to eliminate accumulated drugs, metabolites, and electrolytes from the bloodstream. These methods are particularly vital in cases of accidental poisoning and drug overdose.Hemoperfusion involves passing blood through an adsorbent material to remove unwanted substances. The main adsorbents used in hemoperfusion include activated charcoal and Amberlite resins. Activated charcoal can adsorb both polar and nonpolar...
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Extracorporeal Removal of Drugs: Peritoneal Dialysis and Hemodialysis01:30

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Patients with end-stage renal disease (ESRD) or those experiencing drug overdose often require extracorporeal methods to eliminate accumulated drugs and metabolites. Hemoperfusion, hemofiltration, and dialysis are the primary techniques to rapidly remove harmful substances without disrupting the patient's fluid and electrolyte balance. For those with compromised renal function, dosage adjustments of concurrent medications may be necessary during extracorporeal drug removal.Dialysis is a process...
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Establishment of a Novel Ex Vivo Lung Perfusion System for Rat Lungs After Circulatory Death
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Extracorporeal lung support.

Michael Salna1, Matthew Bacchetta

  • 1aColumbia University College of Physicians and Surgeons bDivision of Cardiothoracic Surgery, Department of Surgery, Columbia University College of Physicians and Surgeons/NewYork-Presbyterian Hospital, New York, New York, USA.

Current Opinion in Anaesthesiology
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Summary
This summary is machine-generated.

Extracorporeal membrane oxygenation (ECMO) for lung support is safe and evolving. Advances allow awake, ambulatory patients and future developments may include artificial lungs.

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Area of Science:

  • Cardiopulmonary support
  • Respiratory failure management
  • Medical device innovation

Background:

  • Extracorporeal membrane oxygenation (ECMO) has a long history of development.
  • Continuous advancements in circuit design and safety have been made since the 1950s.

Observation:

  • ECMO is used for acute respiratory distress syndrome, COPD exacerbations, bridge to transplantation, intraoperative support, and patient transport.
  • Patients on ECMO can now be awake, extubated, and ambulatory, enabling faster recovery or transplant optimization.

Findings:

  • Extracorporeal lung support is a safe and readily implemented treatment for refractory respiratory failure.
  • Recent innovations have expanded ECMO applications beyond acute conditions.

Implications:

  • Future developments in chronic support will drive the creation of durable devices.
  • Ongoing research may lead to the development of artificial lungs, revolutionizing respiratory care.