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Published on: February 14, 2021
Inflammatory bowel disease is associated with hidradenitis suppurativa: Results from a multicenter cross-sectional
Inge E Deckers1, Farida Benhadou2, Marjolein J Koldijk3
1Department of Dermatology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.
Background:
Hidradenitis suppurativa (HS) is often associated with inflammatory bowel disease (IBD; Crohn's disease or ulcerative colitis). However, the prevalence of IBD in HS patients is unknown.
Objective:
To determine the prevalence of IBD in HS patients, and determine if patients with HS and IBD have a distinct HS phenotype.
Methods:
For this multicenter, cross-sectional study, HS patients were asked during their first consultation if they had IBD. The diagnosis of IBD was checked in the medical files, and clinical characteristics were collected.
Results:
IBD had a prevalence of 3.3% (95% CI 2.3-4.4) in 1076 HS patients. The prevalence of Crohn's disease was 2.5% (95% CI 1.6-3.4) and the prevalence of ulcerative colitis was 0.8% (95% CI 0.3-1.4). HS-IBD patients were less frequently obese (13.9% vs 31.2%, P = .04) than HS-only patients, but there were no differences in gender, family history of HS, disease severity, body areas affected by HS, or smoking status.
Limitations:
The prevalence might be underestimated since HS patients might still develop IBD.
Conclusion:
The prevalence of IBD in HS patients (3.3%) is 4-8 times higher than the prevalence in the general northern European population (0.41%-0.74%), however HS-IBD patients do not have a distinct HS phenotype.
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