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Updated: Mar 12, 2026

Monitoring the Cancer-Immunity Cycle and Exploring Tumor Microenvironment Dynamics
Published on: June 7, 2024
Cancer Immunology and Immunotherapy
Ammar Sukari1, Misako Nagasaka2, Ameer Al-Hadidi3
1Karmanos Cancer Institute/Wayne State University School of Medicine, Department of Oncology, Detroit, MI, U.S.A. sukaria@karmanos.org.
Abstract:
Hanahan and Weinberg described six distinct biological properties of cancer cells that enable tumor growth and metastasis. These properties were referred to as the traditional hallmarks of cancer. Recent discoveries further elucidated hallmarks including evasion of immune destruction by tumor cells that disrupt anticancer response pathways. This review discusses cancer immunology and new treatment strategies aimed at restoration of antitumor immune responses.
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