Related Experiment Video
Updated: Mar 12, 2026

Development of a Benchtop Model for Evaluating the Compatibility of Wound Dressing Materials with Negative Pressure Wound Therapy Systems
Published on: May 2, 2025
An evaluation of fluid immersion therapy for the prevention of pressure ulcers
P R Worsley1, B Parsons1, D L Bader1
1Clinical Academic Facility, Faculty of Health Sciences, University of Southampton, Southampton SO16 6QY, UK.
Background:
Individuals with impaired mobility can spend prolonged periods on support surfaces, increasing their risk of developing pressure ulcers. Manufacturers have developed mattresses to maximise contact area. The present study evaluated both the biomechanical and physiological responses to lying postures on a Fluid Immersion Simulation mattress.
Methods:
Seventeen healthy participants were recruited to evaluate the mattress during three prescribed settings of immersion (high, medium and low). Parameters reflecting biomechanical and physiological responses, and the microclimate were monitored during three postures (supine, lateral and high-sitting) over a 90minute test session. Transcutaneous oxygen and carbon dioxide gas responses were categorised according to three criteria and data were compared between each condition.
Findings:
Results indicated that interface pressures remained consistent, with peak sacral values ranging from 21 to 27mmHg across all immersion settings and postures. The majority of participants (82%) exhibited minimal changes in gas tensions at the sacrum during all test conditions. By contrast, three participants exhibited decreased oxygen with increased carbon dioxide tensions for all three immersion settings. Supine and high sitting sacral microclimate values ranged between 30.1-30.6°C and 42.3-44.5% for temperature and relative humidity respectively. During lateral tilt there was a reduction of 1.7-2.5°C and 3.3-5.3% in these values. The majority of participants reported high comfort scores, although a few experienced bottoming out during the high-sitting posture at the high immersion setting.
Interpretation:
Fluid Immersion Simulation provides an intelligent approach to increase the support area. Further research is required to provide evidence based guidance on the use of personalised support surfaces.
Related Concept Videos
Peripheral Artery Disease IV: Nursing Management
Venous Thrombosis IV: Nursing Management
Hand hygiene
Hand washing...
Venous Thrombosis III: Interprofessional Care
Assessment of the Cardiovascular System III: Palpation
Jugular Venous Pressure (JVP) Measurement
Position the patient at a thirty- to forty-five-degree angle or in a semi-fowler's position. Look for the highest point of pulsation in the internal jugular vein and measure the vertical distance to the angle of Loius or sternal angle. A normal JVP is 3-4 cm above...
Fluid Movement Between Compartments

