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Updated: Mar 12, 2026

High-throughput Detection of Respiratory Pathogens in Animal Specimens by Nanoscale PCR
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Complete Genome Sequences of Four Different Bordetella sp. Isolates Causing Human Respiratory Infections

Michael R Weigand1, Yanhui Peng2, Vladimir Loparev2

  • 1Centers for Disease Control and Prevention, Atlanta, Georgia, USA mweigand@cdc.gov.

Genome Announcements
|November 1, 2016
PubMed

Insights

This study presents four complete genome sequences of Bordetella species from human respiratory infections. These findings advance our understanding of Bordetella pathogens causing respiratory illnesses.

Area of Science:

  • Microbiology
  • Genomics
  • Infectious Diseases

Background:

  • The genus Bordetella encompasses species that commonly infect animal hosts, often leading to respiratory disease.
  • Bordetella pertussis is the main cause of whooping cough, with other Bordetella species also implicated in similar respiratory illnesses.

Purpose of the Study:

  • To sequence and analyze the complete genomes of four Bordetella species isolates obtained from human respiratory infections.

Main Methods:

  • Whole-genome sequencing of Bordetella isolates.
  • Bioinformatic analysis of genomic data.

Main Results:

  • Generation of four complete genome sequences for distinct Bordetella species.
  • Characterization of genomic features relevant to host association and pathogenicity.

Conclusions:

  • The availability of these genome sequences provides valuable resources for studying Bordetella evolution and pathogenesis.
  • This work contributes to a deeper understanding of the genetic basis of Bordetella-associated respiratory diseases in humans.

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