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Related Concept Videos

Bone Formation by Intramembranous Ossification01:29

Bone Formation by Intramembranous Ossification

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Intramembranous ossification is one of the two processes involved in the development of bones within an embryo. The flat bones of the face, most of the cranial bones, and the clavicles are formed via this process. During intramembranous ossification, the bones develop directly from sheets of undifferentiated mesenchymal connective tissue.
The process begins when mesenchymal cells in the embryonic skeleton gather together and differentiate into osteogenic cells, which then develop into ...
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Compact Bone01:27

Compact Bone

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Most bones contain compact and spongy osseous tissue, but their distribution and concentration vary based on the bone's overall function.
Compact bone, also called cortical bone, is the denser, stronger of the two types of bone tissue. It is found under the periosteum and in the diaphyses of long bones, where it provides support and protection. The microscopic structural unit of compact bone is called an osteon, or haversian system. Each osteon is composed of concentric rings of calcified...
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Bone Disorders01:29

Bone Disorders

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Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
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Sutures of the Skull01:22

Sutures of the Skull

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The human skull is composed of several bones that come together to protect the brain and support the structures of the face. The junctions where these bones meet are called sutures.
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Bone Formation by Endochondral Ossification01:24

Bone Formation by Endochondral Ossification

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Bone formation, or ossification, begins around the sixth to seventh week of embryonic development. Most bones develop from a cartilaginous template through the process of endochondral ossification. Cartilage formation begins when clusters of mesenchymal cells differentiate into chondrocytes. These chondrocytes proliferate rapidly and secrete an extracellular matrix that becomes encased in a membrane called the perichondrium. The resulting cartilage model provides a template that resembles the...
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Bone Remodeling and Repair01:31

Bone Remodeling and Repair

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Related Experiment Video

Updated: Mar 12, 2026

Lateral Molar Approach-Driven Transoral Endoscopic Procedure for Benign Infratemporal Fossa Tumor Resection
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Lateral Molar Approach-Driven Transoral Endoscopic Procedure for Benign Infratemporal Fossa Tumor Resection

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Peripheral ossifying fibroma: A rare case affecting maxillary region.

Sahana Ashok1, Anish Ashok Gupta1, K P Ashok2

  • 1Department of Oral Pathology and Microbiology, People's Dental Academy, Bhopal, Madhya Pradesh, India.

Indian Journal of Dentistry
|November 1, 2016
PubMed
Summary

Peripheral ossifying fibroma (POF) is a common gingival enlargement, often affecting younger females. Surgical excision is the typical treatment, with a low recurrence rate.

Keywords:
Epulisfocal overgrowthsgingival enlargementsossificationperipheral ossifying fibroma

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Area of Science:

  • Oral pathology
  • Odontogenic tumors
  • Gingival lesions

Background:

  • Focal gingival enlargements present similarly but have diverse causes and histopathology.
  • The etiology of peripheral ossifying fibroma (POF) remains debated.
  • POF typically affects children and young adults, with a slight female predilection.

Observation:

  • This case report details a peripheral ossifying fibroma in the right maxillary posterior region.
  • The lesion was localized, consistent with typical POF presentation.
  • Clinical presentation of focal gingival enlargements can be misleading due to varied etiologies.

Findings:

  • Peripheral ossifying fibroma (POF) is characterized by a benign proliferation of fibrous connective tissue with calcifications.
  • Histopathological examination is crucial for definitive diagnosis.
  • Surgical excision is the primary treatment modality for POF.

Implications:

  • Accurate diagnosis of gingival enlargements is essential for appropriate management.
  • Understanding POF etiology may lead to improved diagnostic or therapeutic strategies.
  • This case contributes to the literature on peripheral ossifying fibroma, highlighting its clinical and pathological features.