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Updated: Mar 12, 2026

Preparation of Primary Acute Lymphoblastic Leukemia Cells in Different Cell Cycle Phases by Centrifugal Elutriation
Published on: November 10, 2017
[Primary plasma cell leukemia: about 3 cases].
Mouhcine Miloudi1, Nezha Messaoudi2
1Laboratoire d'Analyses Médicales, 3ème Hôpital Militaire, Laayoune, Maroc.
Plasma cell leukemia, a rare and aggressive blood cancer, involves high levels of plasma cells. This study details three new cases, offering insights into its clinical and prognostic features.
Area of Science:
- Hematology
- Oncology
- Clinical Pathology
Background:
- Plasma cell leukemia (PCL) is a rare hematologic malignancy.
- It is defined by over 20% plasma cells in the leukocyte count or >2 × 10^9/L circulating plasma cells.
- PCL can be primary (60%) or secondary to multiple myeloma (40%).
Observation:
- This study presents three cases of PCL diagnosed at Mohamed V Military Hospital.
- The rarity of PCL limits the available case reports and clinical data.
- The condition is known for its aggressive nature and poor prognosis.
Findings:
- The study aims to describe the clinical, biological, and prognostic characteristics of PCL.
- Analysis of these three cases will contribute to understanding PCL's presentation and progression.
- Detailed case information will aid in characterizing this rare leukemia.
Implications:
- Understanding PCL's features is crucial for timely diagnosis and treatment.
- Further research into PCL is needed due to its aggressive nature and poor outcomes.
- This case series adds valuable data to the limited literature on plasma cell leukemia.
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