[Primary plasma cell leukemia: about 3 cases]

Plasma cell leukemia is a rare hematologic malignancy defined by the presence of more than 20% of leukocyte count plasma cells or by a number of circulating plasma cells greater than 2 × 10⁹/L (2G/L). It may be primary in 60% of cases and it manifests itself immediately as a leukemia or as a secondary event, in 40% of cases, complicating a previously diagnosed multiple myeloma. Given the rarity of this condition, only a few cases have been reported in the literature. It is characterized by its aggressiveness and poor prognosis. This study reports 3 cases diagnosed in the hematology laboratory of Mohamed V Military Hospital and aims to describe the clinical, biological and prognostic features of this disease.