Related Experiment Video
Updated: Mar 12, 2026

Preparing a Mice Model of Severe Acute Pancreatitis via a Combination of Caerulein and Lipopolysaccharide Intraperitoneal Injection
Published on: May 10, 2024
[Mesenteric panniculitis associated with acute pancreatitis: about a case]
Hedfi Mohamed1, Charfi Mehdi1, Messaoudi Ikram1
1Service de Chirurgie Générale Hôpital Des FSI La Marsa, Tunisie.
Abstract:
Mesenteric panniculitis is a nonspecific inflammation involving the mesentery. Its clinical presentation is variable depending on the stage of the disease. Clinical signs are usually pain but half of the patients remain asymptomatic. Palpable abdominal mass, weight loss, nausea and vomiting. There may be an inflammatory syndrome of variable intensity. Panniculitis is suspected based on scan showing hyperdense mesentery with adhesions to adjacent organs. Histologically there is adipocyte degeneration causing foreign body reaction and appear lymphoplasmacytic inflammatory lesions. We report a new case of mesenteric panniculitis associated with acute pancreatitis.
Insights
Mesenteric panniculitis is a rare condition causing inflammation of the mesentery. This case highlights a new association between mesenteric panniculitis and acute pancreatitis.
Area of Science:
- Gastroenterology
- Pathology
Background:
- Mesenteric panniculitis is a rare, nonspecific inflammatory condition affecting the mesentery.
- Its clinical presentation varies, often including abdominal pain, but can be asymptomatic.
Observation:
- Imaging reveals a hyperdense mesentery with adhesions.
- Histological examination shows adipocyte degeneration and lymphoplasmacytic inflammatory lesions.
Findings:
- This report details a novel case of mesenteric panniculitis occurring concurrently with acute pancreatitis.
Implications:
- This association expands the known clinical spectrum of mesenteric panniculitis.
- Further research may elucidate the pathogenetic link between these conditions.
Related Concept Videos
Acute Pancreatitis II: Clinical Manifestations and Management
Acute Pancreatitis I: Introduction
Acute pancreatitis is characterized by rapid inflammation of the pancreas, often caused by factors like gallstone blockage or excessive alcohol consumption. Chronic pancreatitis, on the other hand, is a slow, progressive inflammation that may result from long-term alcohol abuse, obstructions in the pancreatic duct, or genetic factors.
The causes of acute pancreatitis include:
Chronic Pancreatitis I: Introduction
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
Chronic Pancreatitis II: Collaborative Care
Assessment:
Gastritis-II: Pathophysiology
In acute gastritis, the gastric mucosa becomes swollen and red and undergoes superficial erosion. Superficial ulceration may lead to bleeding.
In chronic gastritis, persistent or repeated insults lead to chronic inflammatory changes and, eventually, thinning or atrophy of the gastric tissue.
Gastritis can stem from various causes, each...

