Related Experiment Video
Updated: Mar 12, 2026

Preparation of Meiotic Chromosome Spreads from Mouse Spermatocytes
Published on: November 22, 2017
Protein and Chromosome Analysis in Mammalian Meiocytes
Michelle Stevense1, Rolf Jessberger2, Attila Tóth2
1Institute of Physiological Chemistry, Medical Faculty Carl Gustav Carus, Technische Universität Dresden, Fiedlerstraße 42, 01307, Dresden, Germany. michelle.stevense@tu-dresden.de.
Abstract:
Meiosis is a highly specialized cell division that facilitates the production of haploid gametes from diploid mother cells. It is characterized by unique chromatin structures and chromatin associated protein complexes. The analysis of these structures and complexes has greatly benefited from and relied on the visualization of meiotic proteins in diverse preparations of meiocytes. In this chapter we summarize methods that can be used for the characterization of the behavior and localization of meiotic proteins in mammalian meiocytes.
More Related Videos
Related Concept Videos
Meiosis vs. Mitosis
Before the start of mitosis and meiosis I, the cell synthesizes DNA, resulting in two homologous copies of each chromosome. DNA synthesis is...
Meiosis II
The timing and cell division patterns of meiosis differ between males and females. In male meiosis, the centrosomes are part of the formation of the meiotic spindle. However, in oocytes, including that of humans, Drosophila,...
Meiosis II
Meiosis I
Meiosis I
Prophase I is the most extended and complex step of meiosis I characterized by synapsis, chromosome pairing, and recombination of the homologous chromosomes. This process is facilitated by a proteinaceous structure called the...
Karyotyping

