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Phaeochromocytoma presenting as an acute coronary syndrome
Towhid Imam1, Philip Finny1,2, Alan Choo-Kang3
1Basildon University Hospital, Basildon, UK.
Insights
A patient with cardiogenic shock and diabetes was diagnosed with a rare adrenal tumor, phaeochromocytoma. Surgical removal led to full recovery, highlighting the importance of considering rare diagnoses for unusual symptoms.
Area of Science:
- Endocrinology
- Cardiology
- Oncology
Background:
- A 44-year-old male with type 2 diabetes, migraine, and anxiety presented with acute cardiogenic shock and pulmonary edema.
- He had recently undergone colonoscopy for colitis and was prescribed prednisolone.
Observation:
- During hospitalization for myocardial infarction, the patient developed abdominal pain.
- A CT scan revealed a large right adrenal mass, and elevated plasma-free metadrenaline levels were detected.
Findings:
- The patient was diagnosed with phaeochromocytoma, a rare adrenal tumor.
- A right adrenalectomy was successfully performed after 4 months.
Implications:
- Successful surgical management normalized cardiac function and resolved diabetes in the patient.
- Delayed diagnosis of phaeochromocytoma due to misattribution of symptoms underscores the need for comprehensive diagnostic evaluation.
- Phaeochromocytoma can present atypically, including with acute coronary syndromes, necessitating awareness among clinicians.
Abstract:
A 44-year-old Caucasian man presented to the emergency department in acute cardiogenic shock, with pulmonary oedema, secondary to an acute myocardial infarction and in a hyperosmolar hyperglycaemic state. The previous day he had undergone a colonoscopy, which revealed features of colitis, and was started on prednisolone. He had been previously diagnosed with type 2 diabetes, migraine and anxiety attacks. While awaiting a coronary angiogram he developed abdominal pain and a CT scan was performed and found a large right adrenal mass. Plasma-free metadrenaline levels were elevated. After 4 months, a right adrenalectomy was performed successfully. He made a good recovery with normalisation of his heart function and resolution of his diabetes. The diagnosis was delayed for years due to his episodic symptoms being attributed to other more common diagnoses. Although a rare diagnosis in itself, there are case reports of phaeochromocytoma initially presenting with an acute coronary syndrome.
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