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Updated: Mar 12, 2026

Imaging of the Microstructural Failure Mechanism in the Human Hip

Imaging of the Microstructural Failure Mechanism in the Human Hip

Published on: September 29, 2023

World Hip Trauma Evaluation (WHiTE): framework for embedded comprehensive cohort studies.

Matthew L Costa¹, Xavier L Griffin¹, Juul Achten¹

¹NDORMS (Nuffield Department of Orthopaedics, Rheumatology, and Musculoskeletal Sciences), Kadoorie Centre, University of Oxford, John Radcliffe Hospital, Oxford, UK.

|November 1, 2016

Summary

Osteoporotic hip fractures are a major global health issue. The World Hip Trauma Evaluation (WHiTE) study comprehensively tracks outcomes for UK hip fracture patients to improve care.

Keywords:

ORTHOPAEDIC & TRAUMA SURGERY TRAUMA MANAGEMENT

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Area of Science:

Geriatric Medicine
Orthopedic Surgery
Public Health

Background:

Osteoporotic hip fractures pose a significant global challenge, impacting patients, clinicians, and healthcare systems.
Hip fractures represent a substantial economic burden, accounting for 1.4% of social and healthcare costs in developed economies.

Purpose of the Study:

To establish the World Hip Trauma Evaluation (WHiTE) cohort for comprehensive outcome measurement in UK hip fracture patients.
To utilize the WHiTE cohort as a platform for embedded observational studies to enhance understanding and treatment of hip fractures.

Main Methods:

The WHiTE study involves a comprehensive cohort of UK patients treated under a unified pathway.
A core outcome set, including health-related quality of life, is collected for all participating patients.
This multicenter project serves as a vehicle for multiple embedded observational studies.

Main Results:

The WHiTE study protocol has been established and approved by relevant ethics and NHS committees.
Ethical approval was granted (Rec reference 11/LO/0927) and NHS approvals obtained.
The study is registered with the National Institute of Health Research Portfolio (UKCRN ID 12351) and ISRCTN registry (ISRCTN63982700).

Conclusions:

The WHiTE study provides a robust framework for evaluating hip fracture patient outcomes.
The comprehensive data collected will facilitate numerous embedded studies to advance hip fracture care.
This initiative aims to improve the management and outcomes for individuals suffering from osteoporotic hip fractures.