World Hip Trauma Evaluation (WHiTE): framework for embedded comprehensive cohort studies
Related Experiment Video
Updated: Mar 12, 2026
Imaging of the Microstructural Failure Mechanism in the Human Hip
Published on: September 29, 2023
Matthew L Costa1, Xavier L Griffin1, Juul Achten1
1NDORMS (Nuffield Department of Orthopaedics, Rheumatology, and Musculoskeletal Sciences), Kadoorie Centre, University of Oxford, John Radcliffe Hospital, Oxford, UK.
Introduction:
Osteoporotic hip fractures present a significant global challenge to patients, clinicians and healthcare systems. It is estimated that hip fracture accounts for 1.4% of total social and healthcare costs in the established market economies.
Methods And Analysis:
The World Hip Trauma Evaluation (WHiTE) was set up to measure outcome in a comprehensive cohort of UK patients with hip fracture. All patients in the cohort are treated under a single comprehensive treatment pathway. A core outcome set, including health-related quality of life, is collected on all the patients. This protocol describes the current multicentre project that will be used as a vehicle to deliver a series of embedded observational studies.
Ethics And Dissemination:
Research Ethics Committee approval was granted (Rec reference 11/LO/0927, approved 18/8/2011) and each hospital trust provided National Health Service (NHS) approvals.
Trial Registration Number:
The study is registered with National Institute of Health Research Portfolio (UKCRN ID 12351) and the ISRCTN registry (ISRCTN63982700).
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