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Updated: Mar 12, 2026

Retinal Pathophysiological Evaluation in a Rat Model
Published on: May 6, 2022
Objective Determination of Retinal Function in Bietti Crystalline Retinopathy
Dorukcan Akıncıoğlu1, Ümit Yolcu2, Abdullah İlhan3
1Gülhane Military Medical Academy, Department of Ophthalmology, Ankara, Turkey.
Abstract:
A 44-year-old female patient without any known systemic or ocular disease presented with progressive visual loss and night vision disturbance. Visual acuity was 0.6 in the right eye and 0.2 in the left eye. Tiny, yellow crystalline deposits were seen on fundus examination. In addition, areas of retinal pigment epithelium and choriocapillaris atrophy were detected. Rod and cone responses were depressed in full-field flash electroretinogram. Multifocal electroretinogram testing showed severe foveal function disturbance with less severe but still depressed responses toward the periphery. Multiple hyperreflective lesions were detected in the retina in optical coherence tomography. We aimed to present the role of ocular electrophysiology by comparing the patient's signs and symptoms with her ocular electrophysiological test results.

