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Updated: Mar 12, 2026

Rapid Fabrication of Custom Microfluidic Devices for Research and Educational Applications

Rapid Fabrication of Custom Microfluidic Devices for Research and Educational Applications

Published on: November 20, 2019

Note: Professional grade microfluidics fabricated simply.

Anna Mohammad¹, Mark Davis², Alexey Aprelev²

¹Department of Chemistry, Drexel University, Philadelphia, Pennsylvania 19104, USA.

The Review of Scientific Instruments

|November 3, 2016

Summary

This summary is machine-generated.

Researchers developed a low-cost method for producing microfluidic devices without a clean room. This technique utilizes LEDs, spin-coaters, and microwave plasma bonding for high-fidelity submicron feature reproduction.

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Last Updated: Mar 12, 2026

Rapid Fabrication of Custom Microfluidic Devices for Research and Educational Applications

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Published on: November 20, 2019

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Multi-step Variable Height Photolithography for Valved Multilayer Microfluidic Devices

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Area of Science:

Materials Science
Engineering
Biotechnology

Background:

Microfluidics is increasingly utilized in research and teaching laboratories.
Establishing microfluidic device production facilities often involves high costs or compromises in quality.

Purpose of the Study:

To present an accessible and cost-effective method for fabricating microfluidic devices.
To demonstrate the production of microfluidic devices without requiring a specialized clean room environment.

Main Methods:

Utilizing light-emitting diodes (LEDs) and spin-coaters for device fabrication.
Employing plasma bonding facilitated by a commercial microwave oven for device assembly.
Achieving submicron feature resolution.

Main Results:

Successful fabrication of microfluidic devices without a clean room.
Demonstrated high-fidelity reproduction of submicron features.
Reduced capital expenditure compared to traditional methods.

Conclusions:

The presented approach offers a viable alternative for microfluidic device production.
This method lowers the barrier to entry for microfluidic research and education.
High-quality microfluidic devices can be produced cost-effectively.