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Diclofenac-Induced Rhabdomyolysis - A Great Masquerader.

G Manigandan¹, M S Seshadri²

¹Consultant Physician, Thirumalai Mission Hospital, Ranipet, Tamil Nadu.

The Journal of the Association of Physicians of India

|November 3, 2016

Summary

This summary is machine-generated.

Diclofenac can cause acute rhabdomyolysis and hypovolemic shock. Prompt medical attention ensures rapid recovery from this serious adverse drug reaction.

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Area of Science:

Pharmacology
Toxicology
Clinical Medicine

Background:

Diclofenac is a widely used nonsteroidal anti-inflammatory drug (NSAID).
NSAIDs carry potential risks, including renal and gastrointestinal adverse effects.
Rhabdomyolysis is a rare but severe condition involving muscle breakdown.

Observation:

A patient presented with symptoms indicative of acute rhabdomyolysis.
The patient had recently been administered diclofenac.
Clinical presentation included signs of hypovolemic shock.

Findings:

The patient's condition was diagnosed as diclofenac-induced acute rhabdomyolysis.
Hypovolemic shock was a critical complication.
Rapid recovery was achieved following timely medical intervention.

Implications:

Highlights a potentially life-threatening adverse effect of diclofenac.
Emphasizes the importance of clinical vigilance for NSAID-associated toxicity.
Supports the judicious and selective use of diclofenac in patient care.