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Related Experiment Videos

Best Practices and Innovations for Managing Codeine Misuse and Dependence.

Ian J Norman1, Michael Bergin, Charles D Parry

  • 1Kings College London, Florence Nightingale Faculty of Nursing & Midwifery, London, United Kingdom.

Journal of Pharmacy & Pharmaceutical Sciences : a Publication of the Canadian Society for Pharmaceutical Sciences, Societe Canadienne Des Sciences Pharmaceutiques
|November 3, 2016
PubMed
Summary

This study identifies best practices and innovations to manage codeine misuse and dependence. Key strategies span product lifecycle, from manufacturing to patient treatment, aiming for safer codeine use.

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Area of Science:

  • Public Health
  • Pharmacovigilance
  • Addiction Medicine

Background:

  • Codeine-containing medicines present a public health challenge due to rising misuse and dependence.
  • Over-the-counter (OTC) availability in some regions exacerbates these issues.
  • Ensuring safe and compliant use while maintaining therapeutic access is critical.

Purpose of the Study:

  • To identify best practices for managing opioid abuse and dependence, with a focus on codeine.
  • To explore innovations addressing challenges in safe codeine use, patient awareness, harm reduction, and treatment.
  • To inform strategies for balancing legitimate therapeutic access with minimizing misuse.

Main Methods:

  • A mixed-methods approach combining scoping review analysis, stakeholder interviews, and expert network inquiries.

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  • Interviews included key national stakeholders from public health, pharmaceutical, regulatory, primary care, and addiction sectors.
  • Data were gathered from Ireland, the United Kingdom, and South Africa to capture diverse regulatory perspectives.
  • Main Results:

    • Best practices and innovations were identified across nine key areas.
    • These areas include manufacturing, product information, responsible prescribing, and monitoring.
    • Further areas encompass pharmacy interventions, workplace safety, online supply, treatment, and professional training.

    Conclusions:

    • Innovations are needed to balance legitimate codeine access with harm reduction.
    • The most significant potential for innovation exists throughout the product's retail lifecycle.
    • Consideration of new strategies is warranted to address the complex challenges of codeine misuse and dependence.