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Serum salicylic acid and fruit and vegetable consumption in obese and normal-weight children: a pilot-study
Carlotta Lassandro1,2, Giuseppe Banderali1, Benedetta Mariani1
1a Department of Paediatrics , San Paolo Hospital , Department of Health Science (DISS) , University of Milan , Milan , Italy.
Insights
This study found that obese children have lower serum salicylic acid (SA) levels than normal-weight children. Fruit and vegetable intake did not correlate with SA levels in either group.
Area of Science:
- Nutritional Science
- Biochemistry
- Pediatric Health
Background:
- Salicylic acid (SA), a plant-derived phenolic compound, is recognized for potential health benefits.
- Understanding factors influencing SA levels, such as diet, is crucial for public health.
- Obesity is a growing concern in pediatric populations, with potential metabolic implications.
Purpose of the Study:
- To investigate the association between serum salicylic acid (SA) levels and fruit and vegetable (FV) consumption in obese versus normal-weight children.
- To compare SA levels and FV intake between obese and normal-weight pediatric groups.
Main Methods:
- Pilot study involving 34 obese and 34 normal-weight children.
- Dietary intake assessed using a 7-day dietary record.
- Serum SA concentrations measured via gas chromatography-mass spectrometry.
Main Results:
- No significant difference in daily fruit and vegetable intake was observed between obese and normal-weight children.
- Obese children exhibited significantly lower serum SA levels compared to normal-weight children.
- Serum SA levels showed no significant association with daily FV intake in either obese or normal-weight children.
Conclusions:
- Obesity in children is linked to reduced serum salicylic acid levels.
- Current fruit and vegetable intake metrics do not appear to correlate with serum SA in this pediatric cohort.
- Further research is warranted to explore the specific types and quantities of fruits and vegetables influencing serum SA.
Abstract:
Salicylic acid (SA), a phenolic compound produced by plants, may play a beneficial role on health. This pilot study evaluated whether there might be an association between serum SA and fruit and vegetable (FV) consumption in obese and normal-weight children. Thirty-four obese children (17 boys and 17 girls) and 34 normal-weight children were recruited. Dietary intake was evaluated by the 7-day dietary record. Serum SA was measured using gas chromatography-mass spectrometry method. FV intake in obese and normal-weight children was not different between groups (175.00 (97.66) g versus 192.29 (90.54) g, p = .455). Obese children had lower serum SA than normal-weight children [mean difference, -0.025; 95% CI (-0.044; -0.006) μmol/L]. Serum SA was not associated with daily intake of FV in obese (p = .111) and normal-weight (p = .092) children. Further studies are needed to evaluate the role of FV on serum SA, taking into account also the quantity and the type.
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