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Updated: Mar 12, 2026

Wholemount In Situ Hybridization for Astyanax Embryos
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Asterixis.

Mark A Ellul1,2, Timothy J Cross3, Andrew J Larner4

  • 1Department of Neurology, The Walton Centre NHS Foundation Trust, Liverpool, UK.

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|November 4, 2016
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Summary
This summary is machine-generated.

Asterixis, a clinical sign first noted in hepatic encephalopathy, is now linked to diverse neurological and medical conditions. This review examines its history, features, and clinical importance.

Keywords:
MYOCLONUSasterixisencephalopathyhepatic encephalopathy

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Area of Science:

  • Neurology
  • Internal Medicine

Background:

  • Asterixis was initially described in the 1940s by Adams and Foley.
  • The condition was first observed in patients suffering from hepatic encephalopathy.

Purpose of the Study:

  • To review the history of asterixis.
  • To describe the characteristics of asterixis.
  • To outline the clinical significance of asterixis.

Main Methods:

  • Literature review.
  • Historical analysis.
  • Clinical case review.

Main Results:

  • Asterixis has been associated with numerous conditions beyond hepatic encephalopathy.
  • The sign is relevant in both neurology and general medicine.

Conclusions:

  • Asterixis is a significant clinical sign with a broad range of potential etiologies.
  • Understanding its history and characteristics is crucial for diagnosis and management.