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Related Concept Videos

Inflammatory Bowel Disease V: Surgical Management01:21

Inflammatory Bowel Disease V: Surgical Management

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Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
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Inflammatory Bowel Disease II: Crohn's Disease01:30

Inflammatory Bowel Disease II: Crohn's Disease

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Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
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Inflammatory Bowel Disease I: Ulcerative Colitis01:27

Inflammatory Bowel Disease I: Ulcerative Colitis

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Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
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Chronic Bowel Disorders: Introduction01:17

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Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
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Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy01:30

Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy

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Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
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Renewal of Intestinal Stem Cells01:23

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The intestinal epithelial lining rapidly renews every 4 to 5 days. The renewal is facilitated by intestinal stem cells (ISCs) located at the base of the crypt– a gland located at the bottom of each villus. ISCs divide asymmetrically to form new stem cells and progenitor daughter cells. The daughter cells are called transit-amplifying (TA) cells which move upwards along the crypt and either differentiate into absorptive cells– the enterocytes or secretory cells– including the...
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Related Experiment Video

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A Mouse Model of Intestinal Partial Obstruction
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Recurrent Obstructive Giant Inflammatory Polyposis of the Colon.

Gaurav Syal1, Vikram Budhraja2

  • 1Division of Gastroenterology and Hepatology, Department of Internal Medicine, University of Arkansas for Medical Sciences, Little Rock, AR.

ACG Case Reports Journal
|November 4, 2016
PubMed
Summary
This summary is machine-generated.

Giant inflammatory polyposis, large polyps in inflammatory bowel disease, can mimic colon cancer. This case highlights recurrent obstruction from giant polyposis in indeterminate colitis despite surgery.

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Area of Science:

  • Gastroenterology
  • Colorectal Surgery
  • Pathology

Background:

  • Inflammatory polyps are common in inflammatory bowel disease (IBD).
  • Giant inflammatory polyposis is defined as inflammatory polyps exceeding 1.5 cm.
  • This condition can present asymptomatically or with significant symptoms like obstruction.

Observation:

  • Giant inflammatory polyposis can be mistaken for colon cancer, leading to unnecessary radical surgeries.
  • A rare case of recurrent symptomatic obstruction due to giant inflammatory polyposis in indeterminate colitis is presented.
  • The patient underwent multiple segmental colectomies without resolution of symptoms.

Findings:

  • This is the first reported case of recurrent giant inflammatory polyposis causing obstruction despite multiple colectomies in indeterminate colitis.
  • The case underscores the challenges in managing complex inflammatory polyposis.
  • Diagnostic and therapeutic strategies for giant inflammatory polyposis require careful consideration.

Implications:

  • Accurate differentiation between giant inflammatory polyposis and malignancy is crucial for appropriate patient management.
  • Recurrent obstruction despite colectomies suggests the need for alternative or more aggressive therapeutic approaches.
  • This case contributes to the understanding of rare complications of inflammatory bowel disease and its management.