Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Atomic Force Microscopy01:08

Atomic Force Microscopy

4.6K
Atomic force microscopy (AFM) is a type of scanning probe microscopy that can analyze topographic details of various specimens like ceramics, glass, polymers, and biological samples. AFM offers over 1000 times more resolution than the optical imaging system. Images generated from AFM are three-dimensional surface profiles, offering an advantage over the flat, two-dimensional images from other imaging techniques.
The AFM Probe
The probe is regarded as the heart of any AFM setup and comprises the...
4.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Hyperbranched Poly(octadecyl Acrylate)s as Lubricant Additive Studied by Resonance Shear Measurement.

Langmuir : the ACS journal of surfaces and colloids·2025
Same author

The viscoelasticity of the rubber-ice interface determined by resonance shear measurement: influence of rubber <i>T</i> <sub>g</sub>.

Science and technology of advanced materials·2025
Same author

Confined Liquids Studied by Resonance Shear Measurement: Molecular Mechanism of Lubrication.

Langmuir : the ACS journal of surfaces and colloids·2025
Same author

Surface Forces Characterization of Concentrated PMMA Brush Layers under Applied Load and Shear.

Langmuir : the ACS journal of surfaces and colloids·2023
Same author

Hypolipidemic and Anti-Inflammatory Effects of <i>Curcuma longa</i>-Derived Bisacurone in High-Fat Diet-Fed Mice.

International journal of molecular sciences·2023
Same author

Effect of vinylene carbonate on SEI formation on LiMn<sub>2</sub>O<sub>4</sub> in carbonate-based electrolytes.

Physical chemistry chemical physics : PCCP·2022

Related Experiment Video

Updated: Mar 12, 2026

Investigating Receptor-ligand Systems of the Cellulosome with AFM-based Single-molecule Force Spectroscopy
11:34

Investigating Receptor-ligand Systems of the Cellulosome with AFM-based Single-molecule Force Spectroscopy

Published on: December 20, 2013

7.8K

Molecular Architecture Studied by the Surface Forces Measurement.

Kazue Kurihara1

  • 1Institute of Multidisciplinary Research for Advanced Materials & Advanced Institute for Materials Research, Tohoku University , Katahira, Aoba-ku, Sendai 980-8577, Japan.

Langmuir : the ACS Journal of Surfaces and Colloids
|November 4, 2016
PubMed
Summary

Surface forces measurement is a powerful tool for understanding molecular interactions and complex matter. New apparatus allows studying opaque samples and electrochemical processes, revealing phenomena at interfaces.

More Related Videos

Investigating Single Molecule Adhesion by Atomic Force Spectroscopy
09:48

Investigating Single Molecule Adhesion by Atomic Force Spectroscopy

Published on: February 27, 2015

10.9K
Covalent Immobilization of Proteins for the Single Molecule Force Spectroscopy
11:13

Covalent Immobilization of Proteins for the Single Molecule Force Spectroscopy

Published on: August 20, 2018

11.7K

Related Experiment Videos

Last Updated: Mar 12, 2026

Investigating Receptor-ligand Systems of the Cellulosome with AFM-based Single-molecule Force Spectroscopy
11:34

Investigating Receptor-ligand Systems of the Cellulosome with AFM-based Single-molecule Force Spectroscopy

Published on: December 20, 2013

7.8K
Investigating Single Molecule Adhesion by Atomic Force Spectroscopy
09:48

Investigating Single Molecule Adhesion by Atomic Force Spectroscopy

Published on: February 27, 2015

10.9K
Covalent Immobilization of Proteins for the Single Molecule Force Spectroscopy
11:13

Covalent Immobilization of Proteins for the Single Molecule Force Spectroscopy

Published on: August 20, 2018

11.7K

Area of Science:

  • Surface science
  • Physical chemistry
  • Materials science

Background:

  • Surface forces measurement is a key technique for probing molecular interactions.
  • Understanding phenomena at solid-liquid interfaces and in soft complex matter is crucial.
  • Previous methods had limitations, especially for opaque samples and electrochemical studies.

Purpose of the Study:

  • To review the utility of surface forces measurement in studying molecular architecture.
  • To highlight advancements in apparatus for opaque samples and electrochemical applications.
  • To showcase diverse applications of surface forces measurement in scientific research.

Main Methods:

  • Utilizing a developed apparatus capable of analyzing opaque samples in various media.
  • Conducting surface forces measurements under controlled electrochemical potentials.
  • Applying the technique to study biological recognition, polyelectrolyte brushes, molecular clusters, and electrode interfaces.

Main Results:

  • Demonstrated the power of surface forces measurement for characterizing soft complex matter and interfacial phenomena.
  • Identified interacting species in biological systems, such as enzyme-substrate interactions.
  • Characterized polyelectrolyte brush behavior, including steric repulsion and density-dependent transitions.
  • Revealed hydrogen-bonded molecular macrocluster formation of adsorbed alcohols and carboxylic acids.
  • Analyzed surface forces between modified electrodes under varying potentials, elucidating effective electrode potentials.

Conclusions:

  • Surface forces measurement is a versatile and powerful technique for investigating molecular architecture and interfacial phenomena.
  • The developed apparatus expands the applicability of surface forces measurement to opaque systems and electrochemistry.
  • This method provides insights into biological recognition, material properties, and electrochemical processes, revealing novel phenomena.