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Related Concept Videos

Pharmacokinetics in Obese Patients: Drug Absorption and Distribution01:25

Pharmacokinetics in Obese Patients: Drug Absorption and Distribution

342
Obesity significantly alters the pharmacokinetic processes of drug absorption and distribution, presenting unique challenges in medical treatment. The increased fat tissue and decreased lean muscle in obese individuals can significantly affect how drugs are absorbed into the body and distributed across different tissues. This alteration can lead to variances in the effectiveness and safety of medications, necessitating adjustments in dosing or drug selection for obese patients.One notable...
342

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[Late sequelae after gastrointestinal surgery in adults].

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Related Experiment Video

Updated: Mar 12, 2026

Techniques of Sleeve Gastrectomy and Modified Roux-en-Y Gastric Bypass in Mice
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[Development and methods of bariatric surgery].

Sara Danshøj Kristensen1, Flemming Hjørne, Frederik Helgstrand

  • 1hugo-dk@hotmail.com.

Ugeskrift for Laeger
|November 4, 2016
PubMed
Summary

Bariatric surgery offers effective weight loss for severe obesity, decreasing mortality. This review details key surgical and endoscopic weight loss procedures and their supporting evidence.

Area of Science:

  • Bariatric and Metabolic Surgery
  • Gastroenterology
  • Obesity Medicine

Background:

  • Severe obesity is a growing global health concern.
  • Bariatric surgery is the most effective documented treatment for severe obesity, reducing mortality.
  • The number of bariatric procedures has significantly increased in recent decades.

Purpose of the Study:

  • To review the most important bariatric surgical and endoscopic techniques for weight loss.
  • To present the evidence supporting these weight loss interventions.

Main Methods:

  • Literature review of bariatric surgical and endoscopic procedures.
  • Analysis of evidence for efficacy and long-term outcomes.

Main Results:

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  • Bariatric surgery is associated with significant weight loss and improved comorbidities.
  • Endoscopic procedures offer less invasive options for weight management.
  • Long-term data is still limited for some newer bariatric techniques.

Conclusions:

  • Bariatric surgical and endoscopic procedures are crucial for managing severe obesity.
  • Continued research is needed to fully understand the long-term consequences of various bariatric interventions.