Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Matrix-Assisted Laser Desorption Ionization (MALDI)01:08

Matrix-Assisted Laser Desorption Ionization (MALDI)

1.3K
Matrix-assisted laser desorption ionization (MALDI) is a powerful analytical technique used in mass spectrometry. It enables the identification and characterization of various biomolecules, including proteins, peptides, nucleic acids, and carbohydrates. MALDI is an ionization technique, widely employed in biological and medical research, as well as in fields like pharmacology and biochemistry.The analyte of interest, a biomolecule or a mixture of biomolecules, is mixed with a suitable matrix...
1.3K
Atomic Emission Spectroscopy: Lab01:29

Atomic Emission Spectroscopy: Lab

759
AES is a powerful analytical technique, especially effective when used with plasma sources, producing abundant spectra in characteristic emission lines. The Inductively Coupled Plasma (ICP), in particular, yields superior quantitative analytical data due to its high stability, low noise, low background, and minimal interferences under optimal experimental conditions. However, newer air-operated microwave sources are emerging as promising alternatives that could be more cost-effective than...
759

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Soluble CD163 in intracerebral hemorrhage: biomarker for perihematomal edema.

Annals of clinical and translational neurology·2017
Same author

Scattering measurement of single particle for highly sensitive homogeneous detection of DNA in serum.

Talanta·2017
Same author

The treatment of femoral neck fracture using VEGF-loaded nanographene coated internal fixation screws.

PloS one·2017
Same author

Splenectomy protects aged mice from injury after experimental stroke.

Neurobiology of aging·2017
Same author

Blockade of α7 nicotinic acetylcholine receptors inhibit nicotine-induced tumor growth and vimentin expression in non-small cell lung cancer through MEK/ERK signaling way.

Oncology reports·2017
Same author

Simultaneous evolutionary expansion and constraint of genomic heterogeneity in multifocal lung cancer.

Nature communications·2017

Related Experiment Video

Updated: Mar 12, 2026

Measurement and Analysis of Atomic Hydrogen and Diatomic Molecular AlO, C2, CN, and TiO Spectra Following Laser-induced Optical Breakdown
09:40

Measurement and Analysis of Atomic Hydrogen and Diatomic Molecular AlO, C2, CN, and TiO Spectra Following Laser-induced Optical Breakdown

Published on: February 14, 2014

14.7K

Digital barcodes of suspension array using laser induced breakdown spectroscopy.

Qinghua He1,2, Yixi Liu1,2, Yonghong He1,2

  • 1Shenzhen Key Laboratory for Minimal Invasive Medical Technologies, Institute of optical imaging and sensing, Graduate School at Shenzhen, Tsinghua University, Shenzhen 518055, China.

Scientific Reports
|November 4, 2016
PubMed
Summary
This summary is machine-generated.

This study introduces a digital coding method for suspension arrays using laser-induced breakdown spectroscopy (LIBS). This technique enhances accuracy and stability for multiplexed detection in life sciences.

More Related Videos

Quantitative Analysis of Vacuum Induction Melting by Laser-induced Breakdown Spectroscopy
03:49

Quantitative Analysis of Vacuum Induction Melting by Laser-induced Breakdown Spectroscopy

Published on: June 10, 2019

7.7K
Dependence of Laser-induced Breakdown Spectroscopy Results on Pulse Energies and Timing Parameters Using Soil Simulants
08:53

Dependence of Laser-induced Breakdown Spectroscopy Results on Pulse Energies and Timing Parameters Using Soil Simulants

Published on: September 23, 2013

11.7K

Related Experiment Videos

Last Updated: Mar 12, 2026

Measurement and Analysis of Atomic Hydrogen and Diatomic Molecular AlO, C2, CN, and TiO Spectra Following Laser-induced Optical Breakdown
09:40

Measurement and Analysis of Atomic Hydrogen and Diatomic Molecular AlO, C2, CN, and TiO Spectra Following Laser-induced Optical Breakdown

Published on: February 14, 2014

14.7K
Quantitative Analysis of Vacuum Induction Melting by Laser-induced Breakdown Spectroscopy
03:49

Quantitative Analysis of Vacuum Induction Melting by Laser-induced Breakdown Spectroscopy

Published on: June 10, 2019

7.7K
Dependence of Laser-induced Breakdown Spectroscopy Results on Pulse Energies and Timing Parameters Using Soil Simulants
08:53

Dependence of Laser-induced Breakdown Spectroscopy Results on Pulse Energies and Timing Parameters Using Soil Simulants

Published on: September 23, 2013

11.7K

Area of Science:

  • Biotechnology
  • Analytical Chemistry
  • Spectroscopy

Background:

  • Suspension arrays are widely used for multiplexed detection in life sciences.
  • Current fluorescent multicolor coding methods suffer from signal crosstalk, affecting accuracy and stability.
  • There is a need for more robust and accurate coding methods for suspension arrays.

Purpose of the Study:

  • To develop a digital coding method for suspension arrays using laser-induced breakdown spectroscopy (LIBS).
  • To transition from analog to digital barcodes for enhanced data encoding.
  • To improve the accuracy, stability, and multiplexing capabilities of suspension arrays.

Main Methods:

  • Preparation of nanocrystal-encoded microspheres using self-assembly encapsulation.
  • Application of laser-induced breakdown spectroscopy (LIBS) for direct read-out of wavelength data.
  • Development of a digital optical barcode system based on LIBS spectral signatures.

Main Results:

  • Demonstrated the feasibility of digital multiplexing using LIBS-based coding.
  • Confirmed that the microspheres can be coded with direct read-out wavelength data.
  • Showed that the LIBS method avoids fluorescence signal crosstalk between barcodes and analyte tags, improving accuracy and stability compared to fluorescent methods.

Conclusions:

  • The developed LIBS-based digital coding method offers significant advantages in accuracy and stability over current fluorescent methods.
  • This approach enhances multiplexed detection and accurate data filtration capabilities.
  • The findings expand the applications of suspension arrays in life science research.