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Updated: Mar 12, 2026

Fabrication, Densification, and Replica Molding of 3D Carbon Nanotube Microstructures
Published on: July 2, 2012
Fabrication of carbon nanotube nanocomposites via layer-by-layer assembly and evaluation in biomedical application
Han Shao1, Peipei Zhao1, Lin Su1
1Key Laboratory of Biomaterials of Guangdong Higher Education Institutes, Department of Biomedical Engineering, College of Life Science and Technology, Jinan University, Guangzhou, Guangdong, 510632, China.
Aim:
To investigate the influence of ion pairing of carboxylated multiwalled carbon nanotubes (MWCNT-COOH) and polycations on the layer-by-layer assembly of nanocomposites and their biocompatibility for biomedical applications.
Materials & Methods:
Strong polycation poly(dimethyldiallylammonium chloride), and weak polycations chitosan and polyethyleneimine were selected to assembly with MWCNT-COOH. The MWCNT-COOH/polycation nanocomposites were analyzed by their physicochemical, electrical properties and biocompatibility.
Results:
The ion pairing of CNTs/polyelectrocytes played a critical role in the layer-by-layer assembly. Strong interactions between MWCNTs and poly(dimethyldiallylammonium chloride) produced thicker nanocomposites with rougher surfaces, higher MWCNT mass and better conductance. All the MWCNT multilayered nanocomposites were of good biocompatibility.
Conclusion:
The MWCNT multilayered nanocomposites hold high potential for biomedical applications.

