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Updated: Mar 12, 2026

Objectification of Tongue Diagnosis in Traditional Medicine, Data Analysis, and Study Application
Published on: April 14, 2023
Host and clinical aspects in patients with benign migratory glossitis
Rafaela Scariot1, Thiago Beltrami Dias Batista2, Marcia Olandoski3
1Universidade Positivo, Curitiba, PR, Brazil.
Objective:
Investigate the association of clinical, cytological and genetic characteristics with benign migratory glossitis (BMG).
Study Design:
Sample consisted of 175 patients, 44 with BMG and 131 control patients. Clinical examination and DMFT index were assessed. Cytological evaluation determined cell morphology and morphometry. Genetic evaluation was performed by analysing IL6 polymorphisms by real-time PCR. Univariate and multivariate analyses were performed (p<0.05).
Results:
There was a higher level of anxiety, DMFT score and a prevalence of fissured tongue in BMG group. A high mean nuclear/cytoplasmic area ratio was observed in patients with BMG. There was predominance of Papanicolaou class II I BMG group. IL6 allele G rs2069843 polymorphism was associated with BMG in the dominant model. In multivariate analysis, DMFT and anxiety scale remained associated with BMG.
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