Genome Sequence of Clostridium paraputrificum 373-A1 Isolated in Chile from a Patient Infected with Clostridium difficile
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Enzo Guerrero-Araya1,2, Angela Plaza-Garrido1,2, Fernando Díaz-Yañez1
1Microbiota-Host Interactions and Clostridia Research Group, Departamento de Ciencias Biológicas, Facultad de Ciencias Biológicas, Universidad Andrés, Bello, Santiago, Chile.
Abstract:
Clostridium paraputrificum is a gut microbiota member reported in several cases of bacteremia and coinfections. So far, only one genome sequence of a C. paraputrificum (AGR2156) isolate is available. Here, we present the draft genome of C. paraputrificum strain 373-A1, isolated from stools from a patient with C. difficile infection.
Insights
We present the first draft genome of Clostridium paraputrificum strain 373-A1, a gut bacterium found in a patient with C. difficile infection. This adds valuable genomic data for this understudied Clostridium species.
Area of Science:
- Microbiology
- Genomics
- Gut Microbiome Research
Background:
- Clostridium paraputrificum is a member of the gut microbiota.
- This species has been implicated in bacteremia and coinfections.
- Only one genome sequence of C. paraputrificum was previously available.
Purpose of the Study:
- To present the draft genome sequence of a novel C. paraputrificum strain.
- To provide a new genomic resource for C. paraputrificum.
Main Methods:
- Isolation of C. paraputrificum strain 373-A1 from human stool samples.
- Whole-genome sequencing and assembly of the C. paraputrificum strain.
Main Results:
- The draft genome sequence of C. paraputrificum strain 373-A1 was successfully generated.
- This represents the second publicly available genome sequence for this species.
Conclusions:
- The availability of this genome sequence enhances the genomic resources for C. paraputrificum.
- This new genomic data will aid further research into the role of C. paraputrificum in the gut microbiome and clinical settings.
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