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Related Concept Videos

Glaucoma: Overview01:25

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Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
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In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
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Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
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Related Experiment Video

Updated: Mar 12, 2026

Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents
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Rates of glaucomatous visual field change after trabeculectomy.

C Baril1, J R Vianna1, L M Shuba1

  • 1Department of Ophthalmology and Visual Sciences, Dalhousie University, Halifax, Nova Scotia, Canada.

The British Journal of Ophthalmology
|November 5, 2016
PubMed
Summary

Trabeculectomy surgery for glaucoma shows similar visual field progression rates to medical treatment. While most patients stabilize, some may still experience vision loss despite successful surgery.

Keywords:
Field of visionGlaucomaIntraocular pressureTreatment MedicalTreatment Surgery

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Area of Science:

  • Ophthalmology
  • Glaucoma Research
  • Surgical Outcomes

Background:

  • Trabeculectomy is a common glaucoma surgery for deteriorating vision.
  • The impact of trabeculectomy on visual field progression is not fully understood.

Purpose of the Study:

  • To compare the rate of visual field progression after trabeculectomy with medically treated glaucoma patients.

Main Methods:

  • Retrospective review of medical records for patients undergoing trabeculectomy.
  • Matched comparison with medically treated glaucoma patients based on baseline visual field loss.
  • Calculation of mean deviation (MD) change rates post-surgery.

Main Results:

  • 180 surgical patients were matched with 180 medically treated patients.
  • Mean follow-up was over 7 years for both groups.
  • No statistically significant difference in MD progression rates between surgical (-0.22 dB/year) and medical (-0.08 dB/year) groups.

Conclusions:

  • Most patients experience slow visual field progression after trabeculectomy, comparable to medical management.
  • Some individuals may progress despite adequate intraocular pressure control post-surgery.
  • Further research is needed to understand progression in specific patient subgroups.