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Updated: Mar 12, 2026

Genome-wide Screen for miRNA Targets Using the MISSION Target ID Library
Published on: April 6, 2012
Genome-Wide miRNA Screening for Genes Bypassing Oncogene-Induced Senescence
Maria V Guijarro1, Amancio Carnero2
1Musculoskeletal and Oncology Lab, Department of Orthopaedics and Rehabilitation, University of Florida, 1600 Archer Road, MSB M2-212, Gainesville, FL, 32610, USA. guijam@ufl.edu.
Abstract:
MicroRNAs are small noncoding RNAs that regulate gene expression by binding to sequences within the 3'-UTR of mRNAs. Genome-wide screens have proven powerful in associating genes with certain phenotypes or signal transduction pathways and thus are valuable tools to define gene function. Here we describe a genome-wide miRNA screening strategy to identify miRNAs that are required to bypass oncogene-induced senescence.
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